Protein Alignment Cyp28c1 and cyp3a4.2

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001015786.1
• Gene: cyp3a4.2 / 548503
• XenbaseID: XB-GENE-971750
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 537
• Identity: 136/537 - (25%)
• Similarity: 234/537 - (43%)
• Gaps: 87/537 - (16%)

  Fly     3 GSLLLGIATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNMIWPRQHFTMDMRDIYMHYRN 67
            |:.:| :|.||..|..:.:..:|::::.|:..|..||..|:|...   |:.......:.:..|..
 Frog    10 GTWIL-LAALLVLILLYGIWPYGYFKKMGIPGPTPLPFIGTFLEF---RKGMVQFDTECFKKYGK 70

  Fly    68 THSYVGCYLLRAPKLLVLEPRLVYEIYV-SAFSHFENNDASKMVDIAKDRLVALN-PF-----VL 125
            ..   |.|..|.|.|.:::|.::..|.| ..:::|.|.           |...|| ||     :.
 Frog    71 MW---GTYDGRQPVLAIMDPAIIKTILVKECYTNFTNR-----------RNFGLNGPFESAITIA 121

  Fly   126 EGEEWRHQRAVFSTLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGG---KDLDCIDLGLRFTGES 187
            |.|:|:..|.|.|...|:|:::....||:    |... |.:|:..|   ||..|....:  .|..
 Frog   122 EDEQWKRIRNVLSPTFTSGKLKEMFQIMK----DYSD-ILVKNIQGYVEKDEPCATKDV--IGAY 179

  Fly   188 LFDCVLGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVHGL------FPNLPRWLRP------ 240
            ..|.   |.:.:|:.|...:.:.:.......:.|...|.:..|      ||    :|||
 Frog   180 SMDV---ITSTSFSVNIDSLNKPSDPFVIHMKKLLKTGLLSPLLILVVIFP----FLRPILEGLN 237

  Fly   241 -KVFPRSHDRFYGQMISEALRLRRSK--HQERNDFINHLLEMQ---------RELDLSEEDMASH 293
             ...|:....|:...:: :.|.:|.|  |..|.|.:..:::.:         :...|::.::.:.
 Frog   238 LNFVPKDFTEFFMNAVT-SFREKRKKGDHSGRVDLLQLMMDSRTTGGNDLSNKHKALTDAEIMAQ 301

  Fly   294 AMTFMFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNES 358
            ::.|:..|.:|||.::::....|..:||.|:||:||:....|....|..|.|:.:.||.....|:
 Frog   302 SVIFIVAGYETTSTALSYLFYNLATHPDVQQRLHEEIDSFLPDKASPTYDILMQMEYLDMVIQET 366

  Fly   359 LRIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFLDG 423
            ||::|..|...:...:..|:.|      :.:..|...::|.|.|..||:.:|||:.||||||
 Frog   367 LRLFPPAGRLERVSKQNVEING------VSIPKGIVTLIPAYVLQRDPEYWPEPEEFRPERF--- 422

  Fly   424 GLKNCKQQG------IFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSPRTLNGTELDPL 482
                .|:..      .||.||:|||.|:|:|..|...|.|:..::|.|.|.....||...|...:
 Frog   423 ----SKENRATHTPFTFLPFGDGPRNCIGLRFALLSMKVAIVTLLQNFSVRPCAETLIPMEFSTI 483

  Fly   483 IFVGVHKGGIWLQFVPR 499
            .|:...| .|.|:|:.|
 Frog   484 GFLQPKK-PIVLKFLSR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	117/465 (25%)
cyp3a4.2	NP_001015786.1	CYP3A	67..495	CDD:410743	119/470 (25%)