Protein Alignment Cyp28c1 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 547
• Identity: 139/547 - (25%)
• Similarity: 243/547 - (44%)
• Gaps: 90/547 - (16%)

  Fly     1 MFGSLLLG----IATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNM---IWPRQHFTMDM 58
            :|.:|.|.    :|.:|..:|.:.....|.::::|:..|:.||..|:..|.   :|     ..||
Mouse     3 LFSALSLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKGLW-----KFDM 62

  Fly    59 RDIYMHYRNTHSYVGCYLLRAPKLLVLEPRLVYEIYV-SAFSHFENND-------ASKMVDIAKD 115
             :.|..|..|.   |.:..:.|..::.:|.::..:.| ..||.|.|..       .||.:.|:||
Mouse    63 -ECYEKYGKTW---GLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKD 123

  Fly   116 RLVALNPFVLEGEEWRHQRAVFSTLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLDCIDLG 180
                        |||:..||:.|...|:|:::....::::....|.:::..::..||.:...|:.
Mouse   124 ------------EEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVL 176

  Fly   181 LRFTGESLFDCVLGIQARTFTDNPLPVVRQNHEMSAENRGL--------AIAGAVHGLFPNLP-- 235
            ..::.:.:.....|:...:..:...|.|.       :.:|:        .:...|  |||.|.
Mouse   177 GAYSIDVITSTSFGVNVDSLNNPEDPFVE-------KAKGILRVDFFDPLVFSVV--LFPFLTPV 232

  Fly   236 -RWLRPKVFPRSHDRFYGQMISEALRLR-RSKHQERNDFI-------NHLLEMQRELDLSEEDMA 291
             ..|...:||:....|:.:.::.....| .||.:.|.||:       |:..:......||:.::.
Mouse   233 YEMLNICMFPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEIT 297

  Fly   292 SHAMTFMFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFN 356
            :.::.|:|.|.:|||::::..|..|..:||.|::|.||:....|....|..|.::::.||....|
Mouse   298 AQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLN 362

  Fly   357 ESLRIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFL 421
            |:||:||.|....:.|.|:.||.|.:      :..|..||:|.||||:||..:|||:.|:||||.
Mouse   363 ETLRLYPIGNRLERFCKKDVELNGVY------IPKGSTVMIPSYALHHDPQHWPEPEEFQPERFS 421

  Fly   422 DGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSPRTLNGTELD------ 480
            ... |......:::.||.|||.|:|||......|.||..::|.|.......|....:|.
Mouse   422 KEN-KGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQ 485

  Fly   481 ---PLIFVGVHKGGIWLQFVPRKNVTT 504
               |::          |:.|||..|.|
Mouse   486 PEKPIV----------LKVVPRDVVIT 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	115/461 (25%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	116/466 (25%)