Protein Alignment Cyp28c1 and Cyp2e1

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_113731.2
• Gene: Cyp2e1 / 25086
• RGDID: 2475
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 127/537 - (23%)
• Similarity: 224/537 - (41%)
• Gaps: 94/537 - (17%)

  Fly     4 SLLLGIATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNMIWPRQHFTMDMRDIYMHYRNT 68
            :||:.:||||  :.:.....:..|..  ...|..||:.|:.         |.:|::||...:...
  Rat     9 ALLVWVATLL--VISIWKQIYNSWNL--PPGPFPLPILGNI---------FQLDLKDIPKSFTKL 60

  Fly    69 HSYVGCYL---LRAPKLLVLEP-RLVYEIYVSAFSHFENNDASKMVDIAKDRLVALNPFVLEGEE 129
            ....|...   |.:.:::||.. :.|.|:.::..:.|.......:....|::.:..|    .|..
  Rat    61 AKRFGPVFTLHLGSRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFN----NGPT 121

  Fly   130 WRHQRAVFSTLLTN---GRIRTTHAIMQRVCLDLCQFIA--IKSAGGKDLD------CIDLGLRF 183
            |:..|....::|.:   |: :...|.:||.    .||:.  :|...|:..|      |....:
  Rat   122 WKDVRRFSLSILRDWGMGK-QGNEARIQRE----AQFLVEELKKTKGQPFDPTFLIGCAPCNV-- 179

  Fly   184 TGESLFDCVLGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVH-GLFPNLPRWLRPKVFPRSH 247
            ..:.||:       :.|..|....:|.   ||..|....:..... .|:.|...:||  ..|.||
  Rat   180 IADILFN-------KRFDYNDKKCLRL---MSLFNENFYLLSTPWIQLYNNFADYLR--YLPGSH 232

  Fly   248 DRFYGQMISEALR--LRRSKHQERNDFIN--------HLLEMQRELDLSE-----EDMASHAMTF 297
            .:.. :.:||..:  |.::|...::..||        .|:||::|....|     |:::......
  Rat   233 RKIM-KNVSEIKQYTLEKAKEHLQSLDINCARDVTDCLLIEMEKEKHSQEPMYTMENVSVTLADL 296

  Fly   298 MFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLR-- 360
            .|.|.:|||.::.:.||:|.:.|:.:.:|:||:..|.....:|.:...:|:||:.|..:|..|
  Rat   297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRVPAVRDRLDMPYMDAVVHEIQRFI 361

  Fly   361 -IYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVP-IYALHNDPDLYPEPDVFRPERFLDG 423
             :.|:.  .....|::...:|       .:.|...|::| :.:|..|...:|:|:.|:||.||:.
  Rat   362 NLVPSN--LPHEATRDTVFQG-------YVIPKGTVVIPTLDSLLYDSHEFPDPEKFKPEHFLNE 417

  Fly   424 GLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEV--VVSPRTLNGTELDPLIFVG 486
            ..| .|....|..|..|.|.|||..|........|:||:|.|.:  :|.|:.:   :|.|   |.
  Rat   418 NGK-FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDI---DLSP---VT 475

  Fly   487 VHKGGIWLQF----VPR 499
            |..|.|..||    :||
  Rat   476 VGFGSIPPQFKLCVIPR 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	107/462 (23%)
Cyp2e1	NP_113731.2	CYP2C-like	64..487	CDD:410758	110/462 (24%)