Protein Alignment Cyp28c1 and Cyp2b23

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001074617.1
• Gene: Cyp2b23 / 243881
• MGIID: 3646735
• Length: 491
• Species: Mus musculus
• Alignment Length: 545
• Identity: 131/545 - (24%)
• Similarity: 222/545 - (40%)
• Gaps: 106/545 - (19%)

  Fly     4 SLLLGIATLLGAIYAFLVSNFGHWRRRGVTE--------PRALPLFGSFPNMIWPRQHFTMDMRD 60
            |:||.:|.|.|.:...:         ||..:        ||.||..|:.         ..||...
Mouse     4 SVLLLLALLTGFLLLLI---------RGQPKAYSRLPPGPRPLPFLGNL---------LQMDRGG 50

  Fly    61 I---YMHYRNTHSYV-GCYLLRAPKLLVLEPRLVYEIYVSAFSHFENNDASKMVD-IAKDRLVAL 120
            :   ::..|:.|..| ..:|...|.:::.....:.|..|.....|....|..::. |.:|..|..
Mouse    51 LLKSFIKLRDKHGDVFTVHLGPRPVVMLYGTETIKEALVDHSDAFSGRGAIAVIQPIVQDYGVIF 115

  Fly   121 NPFVLEGEEWRH-QRAVFSTLLTNGRIRTTHAIMQRVCLDL-CQFIAIKSAGGKDLDCIDLGLRF 183
            :    .||.|:. :|...:|:...|..:  .::.:|:..:. |....:|...|..||...|....
Mouse   116 S----SGERWKTLRRFSLATMRDFGMGK--RSVEERIKEEAQCLVEELKKYEGAPLDPTFLFQCI 174

  Fly   184 TGESLFDCVLGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVHG-LFPNLPRWLRPKVFPRSH 247
            |...:...|.| :...:||:..     .|.:....:.|::..:... ||......|  |.||.:|
Mouse   175 TANIICSIVFG-ERFDYTDHQF-----LHLLDLFYQTLSLISSFSSQLFELFSAVL--KYFPGTH 231

  Fly   248 DRFYGQMISEALR-LRRSKHQER--------NDFIN-HLLEMQRE-----LDLSEEDMASHAMTF 297
             |...:.|.|.|. :..|..|.:        .|||: :||.|::|     .:...:::....::.
Mouse   232 -RQISKNIQEILNYIGHSVEQHKATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHQNLLISVLSL 295

  Fly   298 MFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLR-- 360
            .|.|.:|||.::.:..||:.:.|....::.:|:..|....::|.|:..|.:||..|..:|..|
Mouse   296 FFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVISAHHVPTLEDRIKMPYTEAVIHEIQRFS 360

  Fly   361 -IYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIY--ALHNDPDLYPEPDVFRPERFLD 422
             :.|.|  ...|.||:...||       .|.|.:..:.||.  ||| ||..:.:||.|.||.|||
Mouse   361 DLAPIG--LPHTVTKDTVFRG-------YLLPKNTEVYPILSSALH-DPQYFEQPDKFNPEHFLD 415

  Fly   423 --GGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAAL--AAIVQRF---------EVVVSPRTL 474
              |.||..:   .||.|..|.|.|:|.  |:|..:..|  .|::|.|         ::.::|:..
Mouse   416 ANGALKKSE---AFLPFSTGKRICLGE--GIARNELFLFFTALLQNFSLSSPVAPEDIDLTPKES 475

  Fly   475 NGTELDPLIFVGVHKGGIWLQFVPR 499
            ...::.|     |::    :.|:||
Mouse   476 GFVKIPP-----VYR----ICFLPR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	112/463 (24%)
Cyp2b23	NP_001074617.1	CYP2B	62..486	CDD:410765	112/462 (24%)