Protein Alignment Cyp28c1 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 501
• Identity: 129/501 - (25%)
• Similarity: 222/501 - (44%)
• Gaps: 78/501 - (15%)

  Fly     4 SLLLGIATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNMIWPRQHFTMDMRDIYMHYRNT 68
            :||:.:.||| |.||  :..:..::|.|:..|..:|..|:|.........|.|:.      ::..
 Frog    13 TLLVLLLTLL-AYYA--IWPYKLFKRYGIPGPTPIPFIGTFLGNRHGLMEFDMEC------FKKY 68

  Fly    69 HSYVGCYLLRAPKLLVLEPRLVYEIYV-SAFSHFEN-------NDASKMVDIAKDRLVALNPFVL 125
            ....|.|..:.|.|.:::|.::..|.| ..:::|.|       ......|.|:||
 Frog    69 GKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGLSGPLKSSVLISKD---------- 123

  Fly   126 EGEEWRHQRAVFSTLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLDCIDLGLRFTGESLFD 190
              |:|:..|.|.|...|:|:::....:|......|.:.|..|....:.||.    ....|....|
 Frog   124 --EQWKRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNKEPLDM----KHIFGSYSMD 182

  Fly   191 CVLGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVHGLF----------PNLPR----WLRPK 241
            .||   :.:|:.|...:...|.......|.|......:.||          |.|.:    :|..|
 Frog   183 IVL---STSFSVNVDSMNNPNDPFVTNARNLFTFSFFNPLFLISILCPFLVPLLDKMNFCFLSLK 244

  Fly   242 VFPRSHDRFYGQMISEALRLRRSK--HQERNDFINHLLEMQRE-------------LDLSEEDMA 291
            :.     .|:...:: :::.:|.|  |::|.||:..:::.|..             .:||:.::.
 Frog   245 IL-----NFFKDAVA-SIKKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEEEKHGYKELSDTEIL 303

  Fly   292 SHAMTFMFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFN 356
            :.::.|:..|.:|||.::......:..:||.||:|.||:..:.|....|..|||:.:.|:....|
 Frog   304 AQSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVIN 368

  Fly   357 ESLRIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFL 421
            ||||::|......:.|.|..|:.|      :.:..|..::||::|||.:|:::|||:.|:||||.
 Frog   369 ESLRMFPPAIRIDRVCKKTMEING------VTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFS 427

  Fly   422 DGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEV 467
            ....|| :....||.||.|||.|:|||..|...|.||..::|.|.:
 Frog   428 KENQKN-QDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	113/438 (26%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	113/438 (26%)