Protein Alignment PhKgamma and camk2b

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_012814756.1
• Gene: camk2b / 780379
• XenbaseID: XB-GENE-868398
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 146/516 - (28%)
• Similarity: 226/516 - (43%)
• Gaps: 96/516 - (18%)

  Fly    19 FYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQ 83
            |..:|:..|.:|:|..|.||||::..||.|:|||||:    |:......:..||   :|..|.|
 Frog     8 FTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIIN----TKKLSARDHQKLE---REARICR- 64

  Fly    84 VMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKS 148
            ::.||.|:.|.|....:.|.:|:|:|...||||:.:.:....||......::||.|.|.:.|...
 Frog    65 LLKHPNIVRLHDSISEEGFHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 129

  Fly   149 IVHRDLKPENILLD---ENHNVKITDFGFAKQLQ-EGEKLTNLCGTPGYLAPETLKCNMFEGSPG 209
            :|||||||||:||.   :...||:.|||.|.::| :.:......||||||:||.|:      ...
 Frog   130 VVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR------KEA 188

  Fly   210 YSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVV 274
            |.:.|||||||||::.||||.||||...|..:.:.|..|.|.|.||||..::.:.|:||.:.|.:
 Frog   189 YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTI 253

  Fly   275 DPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPI-APAQTNSRHLLQPEASSYRFGQLNSSCAGAP 338
            :|::|||..|.|:||:..|...:....|....: ...:.|:|..|:        |.:.::.....
 Frog   254 NPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLK--------GAILTTMLATR 310

  Fly   339 NYLYCAPQSSYSSNRMRDGALDDAGASAA-----SATCHVMSPSNASNSYATNTTAN----TSNS 394
            |:       |..........:..|..|.|     ..|..:::.........||:|.|    ||..
 Frog   311 NF-------SVGRQTTAPATITTAATSTALGLVEQGTKSLLNKKTDVGKPQTNSTKNSAGVTSPK 368

  Fly   395 ALASASSHKTLTAMVY-----YQQQPQQHQTQQQQQQYQ-----------------------QQQ 431
            .....::.:|.|.:::     .::......|..:.::.:                       |..
 Frog   369 GPIPPAALETQTTVIHNLVDGIKESSDSTHTNPEDEEMKVMKFSDILSSVRRGSGALEAEGPQAA 433

  Fly   432 TTQLPVQLQLQH-PLLQ------------TGGDGKQSVYA------------PPTVQLRKQ 467
            ..|.|:.....| ||.|            .|.:.:...|:            .|.||.|||
 Frog   434 VAQQPLSPSFPHSPLAQPARFTDIFNTVRRGSEAEGVQYSNTQHRLSQPHLNSPFVQPRKQ 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	110/275 (40%)
camk2b	XP_012814756.1	STKc_CaMKII	10..301	CDD:270988	114/312 (37%)
		CaMKII_AD	492..619	CDD:285524	3/3 (100%)