Protein Alignment PhKgamma and phkg2

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_957256.1
• Gene: phkg2 / 393937
• ZFINID: ZDB-GENE-040426-825
• Length: 390
• Species: Danio rerio
• Alignment Length: 546
• Identity: 223/546 - (40%)
• Similarity: 284/546 - (52%)
• Gaps: 169/546 - (30%)

  Fly     8 DLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLE 72
            |.|||...||.||.||:|||::|||:||.||||:.|.||:|||.|||::.| .:..|.....:..
Zfish     9 DELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQEFAVKIIEITA-EKMTEQQLEEVKS 72

  Fly    73 ATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQI 137
            :|.:||.:|..|.|||.||.|.|.:||.||:||||:|..:||||||||..||||||:||::||.:
Zfish    73 STLKEIHVLNLVKGHPSIITLIDSYESTAFIFLVFDLMRRGELFDYLTEKVTLSEKETRSMMRAL 137

  Fly   138 FEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCN 202
            .|.|:|:||.:||||||||||||||:..::|::||||:.||...|||..|||||||||||.|||:
Zfish   138 LEAVQYLHALNIVHRDLKPENILLDDQGHLKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCS 202

  Fly   203 MFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDL 267
            |.|...||.:|||:||||||:||||.|.||||||||::|||.||||:|.|:||||.|.|:..|||
Zfish   203 MDETHEGYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDL 267

  Fly   268 IRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQPEASSYRFGQLNS 332
            |.:.|||:|:.|:|.::.|.||||
Zfish   268 ISRLLVVEPTIRLTAEQALAHPFF----------------------------------------- 291

  Fly   333 SCAGAPNYLYCAPQSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNSALA 397
                                                  |
Zfish   292 --------------------------------------C-------------------------- 292

  Fly   398 SASSHKTLTAMVYYQQQPQQHQTQQQQQQYQQQQTTQLPVQLQLQHPLLQTGGDGKQSVYAPPTV 462
                                        |||::.                              |
Zfish   293 ----------------------------QYQKED------------------------------V 299

  Fly   463 QLRKQSRFNARKKFQFAILVIRAIIRIRRLRFTAEPLHVEEAIRDPYRVKVLRKVIDGCAFRVYG 527
            :|     |:.||.|:..||.:.|.||::...:.|.||..|...||||.::.:||:|||||||:||
Zfish   300 RL-----FSPRKTFKALILTVLACIRMQCRYYRARPLTKELLSRDPYSIRGVRKLIDGCAFRIYG 359

  Fly   528 HWVKKGEGQNRAALFENTPRTELHAL 553
            |||||||.|||||||:||.:..|..|
Zfish   360 HWVKKGEQQNRAALFQNTAKIILLGL 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	163/271 (60%)
phkg2	NP_957256.1	STKc_PhKG2	13..291	CDD:271083	166/278 (60%)