Protein Alignment PhKgamma and Chek2

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_446129.1
• Gene: Chek2 / 114212
• RGDID: 621543
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 126/317 - (39%)
• Similarity: 178/317 - (56%)
• Gaps: 37/317 - (11%)

  Fly    25 PKEI---------LGRGISSTVRRCIEKETGKEFAAKIID-----LGATTESGETNPYHMLEATR 75
            |||:         ||.|....|:...|::|.|:.|.|||.     ||::.|: :|.|     :..
  Rat   216 PKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREA-DTAP-----SVE 274

  Fly    76 QEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEG 140
            .||.||:: :.||.||.::|||:.:.: ::|.||...|||||.:.....|.|...:....|:...
  Rat   275 TEIEILKK-LNHPCIIKIKDVFDVEDY-YIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLA 337

  Fly   141 VEYIHAKSIVHRDLKPENILL---DENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCN 202
            |:|:|...|:||||||||:||   :|:..:||||||.:|.|.|...:..|||||.|||||.|..|
  Rat   338 VQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISN 402

  Fly   203 MFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRN-IMEGKYSFTSPEWADISEDPKD 266
               |:.|||:.||.|:.|||:|..|.|.|||...|..|.|:: |..|||:.....|.|:||...|
  Rat   403 ---GTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKALD 464

  Fly   267 LIRKCLVVDPSQRITVKEVLRHPFFN--------QMVLMGDRRHPAPPIAPAQTNSR 315
            |::|.|||||..|:|.:|.|.||:..        |.:|:.::.....|:|||||:.:
  Rat   465 LVKKLLVVDPKARLTTEEALSHPWLQDEHMKKKFQDLLVQEKNLVPLPLAPAQTSGQ 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	118/283 (42%)
Chek2	NP_446129.1	FHA_CHK2	96..207	CDD:438718
		STKc_Chk2	216..489	CDD:270986	118/283 (42%)