Protein Alignment PhKgamma and chek2

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_031750712.1
• Gene: chek2 / 100144952
• XenbaseID: XB-GENE-5765421
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 342
• Identity: 125/342 - (36%)
• Similarity: 180/342 - (52%)
• Gaps: 31/342 - (9%)

  Fly     6 EDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHM 70
            :|..:..||    |..||.....:|.|....|:...:|...|:.|.|||.......|..:|.:.:
 Frog   178 DDQTIYPKD----FSDKYIMSRPIGSGACGEVKLAFQKSACKKVAVKIISKRKFKMSTSSNEHPI 238

  Fly    71 LEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMR 135
            ...|  ||.||::: .||.||.:::.|:|:.|.::|.||...|||||.:.|...|.|...:....
 Frog   239 SVDT--EIEILKKI-DHPCIIKIENFFDSEDFFYIVLELMEGGELFDKVVSSTRLRESTAKLYFY 300

  Fly   136 QIFEGVEYIHAKSIVHRDLKPENILLDENHN---VKITDFGFAKQLQEGEKLTNLCGTPGYLAPE 197
            |:...|:|:|...::||||||||:||..::.   :||||||.:|.|.|...:..|||||.|||||
 Frog   301 QMLLAVQYLHENGVIHRDLKPENVLLSSSNEECCIKITDFGQSKILGETSLMRTLCGTPTYLAPE 365

  Fly   198 TLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRN-IMEGKYSFTSPEWADIS 261
            .|..   .|:.|||:.||.|:.|||:|..|.|.|||..:...:.|:| |.||||::....|..:|
 Frog   366 VLNT---AGTTGYSRAVDYWSLGVILFVCLSGYPPFSEQNSKIPLKNQIAEGKYTYIPAAWDAVS 427

  Fly   262 EDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPA-----------PPIAPAQTNSR 315
            |...||::|.|||||.||:|.|:.|.||:...    .|.:|.|           ||.:...|:.:
 Frog   428 EQALDLVKKLLVVDPEQRLTTKQALEHPWLQD----DDMKHTAERLMYGVDHTMPPPSKINTSRK 488

  Fly   316 --HLLQPEASSYRFGQL 330
              |....:||:..|.::
 Frog   489 RGHEWDQDASTSAFSEI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	112/275 (41%)
chek2	XP_031750712.1	FHA_CHK2	64..175	CDD:438718
		STKc_Chk2	184..457	CDD:270986	114/282 (40%)