Protein Alignment Ptp10D and pyp2

DIOPT Version :10

• Sequence 1: NP_996413.2
• Gene: Ptp10D / 32115
• FlyBaseID: FBgn0004370
• Length: 1990
• Species: Drosophila melanogaster
• Sequence 2: NP_594899.1
• Gene: pyp2 / 2542200
• PomBaseID: SPAC19D5.01
• Length: 711
• Species: Schizosaccharomyces pombe
• Alignment Length: 775
• Identity: 176/775 - (22%)
• Similarity: 284/775 - (36%)
• Gaps: 234/775 - (30%)

  Fly   886 LPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV---VRSGTESSVLRSSSPL 947
            |.|.|:|         ..|.:....|.:...|.|||.|..|..:.:   :.....:::||
pombe     5 LSKDEFN---------STLKSFEEQTESVSWIIDLRLHSKYAVSHIKNAINVSLPTALLR----- 55

  Fly   948 SASFTTNEAVPGRVERFHPTDVQPS--EINFEWSLPSSEANGVIRQFSI-------AYTNINNLT 1003
            ..||..     |:|......:|:.|  |||..:...||.| |:.|.:.:       .|:....|.
pombe    56 RPSFDI-----GKVFACIKCNVKVSLDEINAIFLYDSSMA-GMNRIYDLVQKFRRGGYSKKIYLL 114

  Fly  1004 DAGMQDFESEEAFGVIKNLKPGETYVFKIQ---------------AKTAIGFGPEREYRQTMPIL 1053
            ..|.:.|.|.....::......|:..:||.               :..:....|:..:...:||.
pombe   115 SNGFEAFASSHPDAIVSTEMVKESVPYKIDINENCKLDILHLSDPSAVSTPISPDYSFPLRVPIN 179

  Fly  1054 APPRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS 1118
            .||...|..|.::.:                                 ::.||..|.|.:..:..
pombe   180 IPPPLCTPSVVSDTF---------------------------------SEFASHAEYPGFSGLTP 211

  Fly  1119 YSVWLP----------------------YQAIDPYYPFENR--------SVED-----FTIGTEN 1148
            :|:..|                      :||..||:|....        |..|     |.:|
pombe   212 FSIHSPTASSVRSCQSIYGSPLSPPNSAFQAEMPYFPISPAISCASSCPSTPDEQKNFFIVG--- 273

  Fly  1149 CDNHKIGYCNGP--------LKSGTTY----------RVKVRAFTGADKFTDTAYSFPIQTDQDN 1195
                     |.|        |:|..:|          ..:||:|:...|.::..          |
pombe   274 ---------NAPQQTPARPSLRSVPSYPSSNNQRRPSASRVRSFSNYVKSSNVV----------N 319

  Fly  1196 TSLIVAITVPLTIILVLLVTLLFYKRRRN--NCRKTTKDSRANDNMSL--------PDSVIEQNR 1250
            .||..|        .:.::.....||..|  |...:|..|:...::.|        |..:...|:
pombe   320 PSLSQA--------SLEIIPRKSMKRDSNAQNDGTSTMTSKLKPSVGLSNTRDAPKPGGLRRANK 376

  Fly  1251 PILIKN-----FAEHYR-----------------------LMSADSDFRFS--EEFEELKHVG-R 1284
            |...|.     |::..:                       |.:|...::|.  ||.|..:.:. .
pombe   377 PCFNKETKGSIFSKENKGPFTCNPWGAKKVSPPPCEVLADLNTASIFYKFKRLEEMEMTRSLAFN 441

  Fly  1285 DQPCTFADLPCNRP-----KNRFTNILPYDHSRFKLQPVDDDEG-SDYINANYVPGHNSPREFIV 1343
            |....:..|..:|.     |||:|:|:|||.:|.:|..   .:| ||||||:::...|  :::|.
pombe   442 DSKSDWCCLASSRSTSISRKNRYTDIVPYDKTRVRLAV---PKGCSDYINASHIDVGN--KKYIA 501

  Fly  1344 TQGPLHSTRDDFWRMCWESN--SRAIVMLTRCFEKGREKCDQYWPN--DTVPVFYGDIKVQILND 1404
            .|.|...|..|||.|.|.::  :..|||||..:|.|.|||.||||:  |......|.:::.:...
pombe   502 CQAPKPGTLLDFWEMVWHNSGTNGVIVMLTNLYEAGSEKCSQYWPDNKDHALCLEGGLRISVQKY 566

  Fly  1405 SHYADWVMTE--FMLCR-GSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVV 1466
            ..:.|..:..  |.|.: ....:.:.||...||.|...|: .:::...:|.. |:: ....|:.|
pombe   567 ETFEDLKVNTHLFRLDKPNGPPKYIHHFWVHTWFDKTHPD-IESITGIIRCI-DKV-PNDGPMFV 628

  Fly  1467 HCSAGVGRSGTFITLDRILQ--------QINTSDYVD-IFGIVYAMRKERVWMVQTEQQY 1517
            ||||||||:||||.:|:|||        ..|..|..| ||..|.::|.:|:.|||..:|:
pombe   629 HCSAGVGRTGTFIAVDQILQVPKNILPKTTNLEDSKDFIFNCVNSLRSQRMKMVQNFEQF 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:394996
		fn3	220..304	CDD:394996
		FN3	278..>734	CDD:442628
		FN3	583..671	CDD:238020
		fn3	787..850	CDD:394996
		fn3	866..935	CDD:394996	12/51 (24%)
		fn3	959..1043	CDD:394996	20/107 (19%)
		PTP_tm	1083..1187	CDD:465889	24/156 (15%)
		R3-PTPc	1301..1522	CDD:350396	82/234 (35%)
pyp2	NP_594899.1	DSP_MapKP	4..129	CDD:238723	33/143 (23%)
		PHA03247	<159..304	CDD:223021	27/189 (14%)
		PTP_fungal	486..693	CDD:350509	71/208 (34%)