Protein Alignment HOXB1 and Antp

DIOPT Version :10

• Sequence 1: NP_002135.2
• Gene: HOXB1 / 3211
• HGNCID: 5111
• Length: 301
• Species: Homo sapiens
• Sequence 2: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 102/358 - (28%)
• Similarity: 128/358 - (35%)
• Gaps: 97/358 - (27%)

Human     1 MDYNRMNSFLEYPLCN-RGPSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQ----- 59
            |.|.|...:...|..| :|......|.. .|.|.|.:..|.....:.:..|.|..|..||
  Fly    55 MPYPRFPPYDRMPYYNGQGMDQQQQHQV-YSRPDSPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQ 118

Human    60 ----NSGYPAQQPPSTLGVPFP------------SSAPSGYAPAACSPSYGPSQYYPLGQS---- 104
                .....|||.|..|....|            ...|..||......:.|.....|.|.|
  Fly   119 PSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLV 183

Human   105 -EGDGGYF-----------HPSSYGAQLG----GLSD-------GYGAG------GAGPGPYPPQ 140
             :..|.:.           ||.   ||||    |:.|       .:..|      |..|...|||
  Fly   184 DQMSGHHMNAQMTLPHHMGHPQ---AQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQ 245

Human   141 ---HPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPT----ARTFDWMKVKRNPPKTAKVSEP 198
               |...|..|.....|.        :.||....||:.:    :..:.||:     .:..|..|.
  Fly   246 GMMHQGQGPPQMHQGHPG--------QHTPPSQNPNSQSSGMPSPLYPWMR-----SQFGKCQER 297

Human   199 GLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKRER 263
            ..|     |..:|..|..|||||||||:||:|.||:|||..|.|.|.|:||||||||||.||..:
  Fly   298 KRG-----RQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENK 357

Human   264 EEGRVPPAPPGCPKEAAGDASDQSTCTSPEASP 296
            .:|.     ||     :|...|:.|   |..||
  Fly   358 TKGE-----PG-----SGGEGDEIT---PPNSP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB1	NP_002135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..77		15/65 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..149		8/30 (27%)
		Antp-type hexapeptide	179..184		1/4 (25%)
		Homeodomain	207..260	CDD:459649	34/52 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..301		15/43 (35%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	33/165 (20%)
		Homeodomain	298..354	CDD:459649	35/60 (58%)