Protein Alignment Polr2A and rpoC1

DIOPT Version :10

• Sequence 1: NP_511124.1
• Gene: Polr2A / 32100
• FlyBaseID: FBgn0003277
• Length: 1887
• Species: Drosophila melanogaster
• Sequence 2: NP_051050.1
• Gene: rpoC1 / 844784
• -ID: -
• Length: 680
• Species: Arabidopsis thaliana
• Alignment Length: 797
• Identity: 174/797 - (21%)
• Similarity: 282/797 - (35%)
• Gaps: 246/797 - (30%)

  Fly    15 KRVQFGILSPDEIRRMS---------VTEGGVQFAETMEGGRPKLGGLMDPRQGVIDRTSRCQTC 70
            ::::.|::||.:|...:         |.|....:....:..:|:..||...|   |....:...|
plant     8 QQLRIGLVSPQQISAWATKIIPNGEIVGEVTKPYTFHYKTNKPEKDGLFCER---IFGPIKSGIC 69

  Fly    71 A-GN-------------MTECPGHF----------GHIDLAKPVFHIGF-----------ITKTI 100
            | ||             ..:|...|          |:|.|..||.|:.:           :.|.:
plant    70 ACGNYRVIGDEKEDPKFCEQCGVEFVDSRIRRYQMGYIKLTCPVTHVWYLKRLPSYIANLLDKPL 134

  Fly   101 KILRCVCFYCSKMLVSPHNPKIKEIVMKSRGQPRKRLAYVYDLCKGK-----TICEGGEDMDLTK 160
            |.|..: .||......|...  |...::.||      ::.|::...|     .....|.|:...:
plant   135 KELEGL-VYCDFSFARPITK--KPTFLRLRG------SFEYEIQSWKYSIPLFFTTQGFDIFRNR 190

  Fly   161 ENQQPDPNKKPGHGGCGHYQPSIRRTGLDL-------TAEWKHQNEDS------QEKKIVVSAE- 211
            |...          |.|..:..:  ..|||       ..|||...|:.      :::|||...:
plant   191 EIST----------GAGAIREQL--ADLDLRIIIENSLVEWKQLGEEGPTGNEWEDRKIVRRKDF 243

  Fly   212 --RVWEILKHI--TDEECFILGMDPKYARPDWMIVTVLPVPPLAVRPAVVMFGAAKNQDDLTHKL 272
              |..|:.||.  |:.|            |:||::.:|||.|..:||.:.:.|......|:....
plant   244 LVRRMELAKHFIRTNIE------------PEWMVLCLLPVLPPELRPIIQIEGGKLMSSDINELY 296

  Fly   273 SDIIKANNELRK--NEASGAAAHVIQENIKMLQFHVATLVDNDMPGMPRAMQKSG--KPLKAIKA 333
            ..:|..||.|..  ..:......::....|::|..|.||:||.:.|.|   .:.|  |..|:...
plant   297 RRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQP---MRDGHNKVYKSFSD 358

  Fly   334 RLKGKEGRIRGNLMGKRVDFSARTVITPDPNLRIDQVGVPRSIAQNLTFPELVTPFNIDRMQELV 398
            .::|||||.|..|:|||||:|.|:||...|:|.:.:.|:||.||             |:..|..|
plant   359 VIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIA-------------IELFQTFV 410

  Fly   399 RRG-------------NSQYPGAKYIVRDNGERIDLRFHPKSSDLHLQCGYKVERHLRDDDLVIF 450
            .||             .||....|.||.:..:.: ::.||                      |:.
plant   411 IRGLIRQHLASNIGVAKSQIREKKPIVWEILQEV-MQGHP----------------------VLL 452

  Fly   451 NRQPTLHKMSMMGHRVKVLPWSTFRMNLSCTSPYNADFDGDEMNLHVPQSMETRAEVENIHITPR 515
            ||.||||::.:...:..::...|..::......:|||||||:|.:|||.|:|.:||...:..:..
plant   453 NRAPTLHRLGIQSFQPILVEGRTICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHM 517

  Fly   516 QIITPQANKPVMGIVQDTLTAVRKM---TKRDVFITREQVMNLL------------------MFL 559
            .:::|....|:....||.|..:..:   |:|.:...|....|..                  .|.
plant   518 NLLSPAIGDPISVPTQDMLIGLYVLTSGTRRGICANRYNPCNRKNYQNERIYETNYKYTKEPFFC 582

  Fly   560 PTWDA--KMPQPCILKPRPLWTGKQIFSLIIPGNVNMIRTHSTHPDEEDEGPYKWISPGDTKVMV 622
            .::||  ...|..|....|||...|:...:|......|..|           |:
plant   583 NSYDAIGAYRQKKINLDSPLWLRWQLDQRVIASREVPIEVH-----------YE----------- 625

  Fly   623 EHGELIMGILCKKSLGTSAGSLLHICFLELGHDIAGRFYGNIQTVINNWLLF-----EGHSIGIG 682
                                                 .:||...:..::|:.     |...|.|.
plant   626 -------------------------------------SFGNYHEIYAHYLIVRSVKKENFCIYIR 653

  Fly   683 DTIADPQTYNEIQQAIK 699
            .|:.....|.||::||:
plant   654 TTVGHISFYREIEEAIQ 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr2A	NP_511124.1	RNAP_II_RPB1_N	15..868	CDD:259848	174/797 (22%)
		RNA_pol_Rpb1_6	890..1071	CDD:461511
		RNAP_II_Rpb1_C	1050..1468	CDD:132720
		Herpes_BLLF1	<1498..1862	CDD:282904
		PTZ00449	<1707..1880	CDD:185628
rpoC1	NP_051050.1	rpoC1	1..675	CDD:214336	174/797 (22%)