Protein Alignment CG43155 and kcnk2a

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_021323122.1
• Gene: kcnk2a / 559728
• ZFINID: ZDB-GENE-061226-2
• Length: 426
• Species: Danio rerio
• Alignment Length: 330
• Identity: 92/330 - (27%)
• Similarity: 140/330 - (42%)
• Gaps: 83/330 - (25%)

  Fly    57 MKWKSALNHIGLLVSLSIYCGVGGLIFRHLERPAE--------VERLSHLKDIVKTHRERFLHTI 113
            ||||:.| .|.|||.|  |..:|..:|:.||:|.|        .|::..|.          :||.
Zfish    55 MKWKTVL-AIFLLVVL--YLIIGATVFKALEQPEEGLQKYRIIQEKIDFLS----------MHTC 106

  Fly   114 LNNTEVHNLDELLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGY 178
            :|.:|   |::|:...:....|.|..:....          .....|.:..:.||:.||:||||:
Zfish   107 VNTSE---LEDLVKQVVLAIRAGVNPSGHPS----------NESSMWDLSSSFFFAGTVITTIGF 158

  Fly   179 GNIVPVTTGGRVFCICFALIGIPFTLTVIADWGRLFATAVSVFGKHM-------------PTKPK 230
            ||:.|.|.|||:|||.:||:|||....::|..|....|   :|||.:             .||.:
Zfish   159 GNVSPHTEGGRIFCIIYALLGIPLFGFLLAGVGDQLGT---IFGKGIAKVEKMFVKWNVSQTKIR 220

  Fly   231 FTNFIGKTWFYAILAVGFLGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVPKKPN- 294
            .|:        .:|.:.|..:...|...|:....:.|:..:..||..||:|||||||.|.....
Zfish   221 VTS--------TVLFILFGCLLFVALPALIFQHIEGWSALESIYFVVITLTTIGFGDFVAGGSEI 277

  Fly   295 -----YMLLCTLYILIGLALTSTIIELVR-----------------RQYATSWAKLQELSGPMAE 337
                 |..:...:||:|||..:.::.::.                 |.:|..|.  ..:|....|
Zfish   278 EYLDYYKPIVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWT--ANVSAEFKE 340

  Fly   338 TLRRL 342
            |.|||
Zfish   341 TRRRL 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	26/70 (37%)
		Ion_trans_2	<267..319	CDD:462301	19/74 (26%)
kcnk2a	XP_021323122.1	Ion_trans_2	<136..194	CDD:462301	26/57 (46%)
		Ion_trans_2	232..310	CDD:462301	21/77 (27%)