DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43155 and Lar

DIOPT Version :9

Sequence 1:NP_572720.2 Gene:CG43155 / 32092 FlyBaseID:FBgn0262685 Length:411 Species:Drosophila melanogaster
Sequence 2:NP_001260594.1 Gene:Lar / 35259 FlyBaseID:FBgn0000464 Length:2032 Species:Drosophila melanogaster


Alignment Length:368 Identity:65/368 - (17%)
Similarity:121/368 - (32%) Gaps:129/368 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 RRVDAAEGGGLAKGTAGGRRSTACW-------QSMKWKSALNHIGLLVSL--------------- 72
            |.:...|.|.:....:.|...|.|:       :.||.:..::..|.:..|               
  Fly  1659 RALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYI 1723

  Fly    73 --------SIYCGVGGL----IFRHLER-------------PAEVERLSHLK-DIVK-------- 103
                    :|.|||..:    :..||::             ..|.::||::| |..|        
  Fly  1724 FIHDAILEAIICGVTEVPARNLHTHLQKLLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPC 1788

  Fly   104 -THRERFLHTI------LNNTEVHNLDEL----LSF-ELAKYEAA-------VQQAAE------- 142
             .|:.|.:|.:      :..|.:|.::..    .|| :..:|.:|       ||.|||       
  Fly  1789 NKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLW 1853

  Fly   143 --GGLLIVADKDFPEP-----YERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICFALIGI 200
              ...::|......|.     ::.|...::|.:...|:..|...|:.....  |.|.:..|..|.
  Fly  1854 EHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKL--REFKVTDARDGS 1916

  Fly   201 PFTLT--VIADW----------------GRLFATAVSVFGKHMPTKPKFTNFIGKTWFYAILAV- 246
            ..|:.  ...||                |::..|. ..||:..|.....:..:|::..:..|:: 
  Fly  1917 SRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTK-EQFGQDGPITVHCSAGVGRSGVFITLSIV 1980

  Fly   247 -------GFLGVY-----LAAGAGLLLLWEDDWTFFDGFYFCF 277
                   |.|.|:     |.:....::..||.      ::||:
  Fly  1981 LERMQYEGVLDVFQTVRILRSQRPAMVQTEDQ------YHFCY 2017

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43155NP_572720.2 Ion_trans_2 <157..214 CDD:285168 13/74 (18%)
Ion_trans <240..314 CDD:278921 9/51 (18%)
Ion_trans_2 <266..319 CDD:285168 2/12 (17%)
LarNP_001260594.1 Ig 35..129 CDD:299845
I-set 36..129 CDD:254352
IG_like 146..227 CDD:214653
Ig 159..228 CDD:299845
I-set 234..318 CDD:254352
Ig3_RPTP_IIa_LAR_like 249..317 CDD:143216
fn3 324..404 CDD:278470
FN3 423..514 CDD:238020
FN3 520..610 CDD:238020
FN3 616..707 CDD:238020
FN3 712..810 CDD:238020
FN3 832..907 CDD:238020
FN3 914..1005 CDD:238020
FN3 1012..1101 CDD:238020
fn3 1106..1198 CDD:278470
PTPc 1476..1731 CDD:214550 10/71 (14%)
PTPc 1503..1731 CDD:238006 10/71 (14%)
PTPc 1763..2022 CDD:214550 49/264 (19%)
PTPc 1791..2022 CDD:238006 43/236 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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