DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43155 and twk-29

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001021467.1	Gene:	twk-29 / 185828	WormBaseID:	WBGene00006681	Length:	476	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	72/272 - (26%)
Similarity:	127/272 - (46%)	Gaps:	35/272 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 CWQSMKWKSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNT 117
            |.|..:...|:|.. ::|.|.||..:||.||.:.    |.|...::|......:...:.::||.
Worm    41 CLQHNRRAIAVNGF-IIVFLIIYTTIGGFIFLNF----EFEYQQYMKQNATLEKRLCIESLLNR- 99

  Fly   118 EVHNLDELLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYE----RWSILQAVFFSSTVLTTIGY 178
                 |..|....|...||.          :|::...|..:    :||...|..:|..:|||:||
Worm   100 -----DNRLRLTRASDVAAA----------IAERCLTENVKDDRMQWSFKSAALYSLGILTTLGY 149

  Fly   179 GNIVPVTTGGRVFCICFALIGIPFTLTVIADWGRLFATAVSVFGKHMPTK----PKFTNFIGKTW 239
            |.|.|.|..||:..:.:...|||.|:.::.::||......:.|.:.:..:    .:..|..|.|.
Worm   150 GKIEPQTINGRISTVIYGFFGIPLTVILLTNFGRYLEAMATRFRRLISCRRRREDEDENVSGSTL 214

  Fly   240 FYAILAVGFLGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVPKKPNYMLLCTLYIL 304
            |:.:|      |||..||.::.|....:.||:|.|:.||.:|.|.:||::|:...::.:...|:.
Worm   215 FFIVL------VYLILGATMIPLMSGQFDFFNGIYYAFICLTAIEYGDIIPQNNWFLPISVFYMC 273

  Fly   305 IGLALTSTIIEL 316
            .|||:::..:::
Worm   274 TGLAISTIALDI 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	21/60 (35%)
		Ion_trans	<240..314	CDD:278921	23/73 (32%)
		Ion_trans_2	<266..319	CDD:285168	15/51 (29%)
twk-29	NP_001021467.1	Ion_trans_2	127..186	CDD:285168	21/58 (36%)
twk-29	NP_001021467.1	Ion_trans_2	216..292	CDD:285168	22/76 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020