Protein Alignment CG43155 and twk-35

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_508031.3
• Gene: twk-35 / 185149
• WormBaseID: WBGene00006687
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 479
• Identity: 116/479 - (24%)
• Similarity: 187/479 - (39%)
• Gaps: 123/479 - (25%)

  Fly     6 VTVKEYDSQDEASTELLEKLKHLDRRVDAAE--GGGLAKGTAG-----------GRRSTACWQSM 57
            |.|..:...|.:.:......:|:.:.|:..:  .|.:.||.||           |:|.....|..
 Worm    60 VVVPTHYKADGSLSRTASNRRHVFQSVNLLQRANGQMRKGAAGVWDIAGRAHLAGKRKVEQLQQK 124

  Fly    58 K--W---------KSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHR----E 107
            .  |         |..|.|..|::...|||..|||:|..:|.|.:.|.....:..::.:|    :
 Worm   125 PPLWLVILNQAYHKYGLKHAVLIIVFLIYCISGGLVFWLIEEPYQSELRDAWQHKIENNRTARVD 189

  Fly   108 RFLHTILNNTEV------HNLDELLSF---ELAKYEAAV-----QQAAEGGLLIVADKDFPEPYE 158
            ..:..|.||::.      :....|.:|   ||..||..:     ||..:
 Worm   190 AMMKKIFNNSDYLIYIKGNTSQRLTTFFIEELGSYENQLGVKWSQQKMD---------------- 238

  Fly   159 RWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICFALIGIPFTLTVIADWGRLFATAVSVFGK 223
             |....||.|:.|:.||||||:|.|:|..||:..:.|||.|||..|.|:.|:|:|....:
 Worm   239 -WDFWNAVLFAGTICTTIGYGHIYPMTDAGRMLTMIFALFGIPLMLLVLQDFGKLLTITM----- 297

  Fly   224 HMPTKPKFTNFIGKTWFYAILA--------------------VGFLGVYLAAGAGLLL------- 261
                  ||..|..|.....|:.                    :....:.|..|..|::
 Worm   298 ------KFPWFQTKRLMRRIMRCCTKQPIEEMKEIERQERHDLDIFDLPLPVGIALIVTWIFICS 356

  Fly   262 ----LWEDDWTFFDGFYFCFITMTTIGFGDLVPKKPNYMLLCTLYILIGLALTSTIIELVRRQYA 322
                :|:.:||..:.|||.|.:::|:|.|||||..|..::....:||:||:|.|.:|.|::.:..
 Worm   357 FVLSVWDHNWTLLESFYFFFTSLSTVGLGDLVPSSPRLLITMFGFILVGLSLVSMVINLLQAKMK 421

  Fly   323 TSWAKLQELSGPMAETLRRLGETAGTGLDYTALQKVLTVSMPKWNSKKNEHSPDIAALEAITNAI 387
            :::.     :|...|....:.:|..|.|.      ||....|. ..||.::|....:....|:..
 Worm   422 STYE-----AGRNDEKTPHIHQTLPTSLG------VLQCFSPD-EEKKTDYSERSLSRSTQTSLS 474

  Fly   388 LKEVKEAQNNKPKVLQIVIYESSV 411
            |          |.|.|:|:....|
 Worm   475 L----------PGVRQVVLRSDGV 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	26/70 (37%)
		Ion_trans_2	<267..319	CDD:462301	22/51 (43%)
twk-35	NP_508031.3	Ion_trans_2	230..294	CDD:462301	29/80 (36%)
		Ion_trans_2	345..420	CDD:462301	24/74 (32%)