DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43155 and kcng4

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_002934997.1	Gene:	kcng4 / 100497160	XenbaseID:	XB-GENE-985941	Length:	506	Species:	Xenopus tropicalis

Alignment Length:	194	Identity:	40/194 - (20%)
Similarity:	74/194 - (38%)	Gaps:	62/194 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 TAC--WQSMK--------------WKSALNHIGLLVSLSIYCGVGGLIF----RHLERPAEVERL 95
            |.|  |.|::              :|..||.|.:|..|..|.   .||.    :.:::|:....|
Frog   265 TICVAWFSLEFFLRFIQAKSKCQFFKGPLNIIDVLAILPYYV---SLIVEDEQKTVDKPSSNSYL 326

  Fly    96 SHLKDIVKTHRE-RFLHTILNNTEVHNLDELLSFELAKYEAAVQQ--------AAEGGLLI---- 147
            ..:..:::..|. |.|:.:               .||::...:|.        ..|.|||:
Frog   327 EKIGLVLRVLRALRILYVM---------------RLARHSLGLQTLGLTVRRCTREFGLLLLFLC 376

  Fly   148 -----------VADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICFALIGI 200
                       :|:.:.....|..|:..:.:::...:||:|||::||.:..|:|..:...|.||
Frog   377 VAVTLFAPLVHLAENEMGRCQEFTSVPASYWWAIISMTTVGYGDMVPRSIPGQVVALSSILSGI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	14/44 (32%)
		Ion_trans	<240..314	CDD:278921
		Ion_trans_2	<266..319	CDD:285168
kcng4	XP_002934997.1	BTB_POZ_KCNG4	59..170	CDD:349730
kcng4	XP_002934997.1	Ion_trans	219..462	CDD:366146	40/194 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000