DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43155 and kcns1

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_002938059.3	Gene:	kcns1 / 100492665	XenbaseID:	XB-GENE-6051189	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	379	Identity:	73/379 - (19%)
Similarity:	148/379 - (39%)	Gaps:	90/379 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KEYDSQDEAST--ELLEKLKHLDRRV---DAAEGGGLAKGTAGGRRSTACWQSM---------KW 59
            :.:|...:||:  ..::::...::.:   |..:.|.|.|         ..|.:|         |.
Frog   132 RNWDEDSDASSIETSVDEISDFNQDIMYFDNVQCGNLRK---------RLWLTMENPGYSIPSKI 187

  Fly    60 KSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLD- 123
            .|.::...:|:|:|..|         :....|.:::.  :|:..          :::..:|.|:
Frog   188 FSFISICVVLISISTMC---------INSMPEYQQVD--EDLAP----------VDDPILHKLEY 231

  Fly   124 ---ELLSFELAKYEAAVQQAAEGGLLIVAD--KDFPEPYERWSILQAVFFSSTVLTTIGYGNIVP 183
               ...:||::           ..||:..:  |.|..|.....|:..:.|..|:...:.:|:...
Frog   232 FCISWFTFEVS-----------SRLLLAPNLKKFFRHPLNLIDIVSVLPFYITLFIDLTFGSDYE 285

  Fly   184 VTTGGRVFCICFALIGIPFTLTVIADWGRLFATAVSVFGKHMPTKPKFTNFIGKTWFYAILAVGF 248
            :...|:|..: |.|:             |:|  .|....:|...    ...:|.|..::...||.
Frog   286 LGNVGKVVQV-FRLM-------------RIF--RVLKLARHSTG----LRSLGATLKHSYREVGI 330

  Fly   249 LGVYLAAG----AGLLLLWE-DDWTFFDGFYFCF----ITMTTIGFGDLVPKKPNYMLLCTLYIL 304
            |.:|||.|    :|:....| |:.|.||....|:    ::|||:|:||:||......|..:..||
Frog   331 LLLYLAVGVSVFSGMAYTAEMDEDTGFDTIPSCWWWGTVSMTTVGYGDVVPVTVAGKLAASGCIL 395

  Fly   305 IGLALTSTIIELVRRQYATSWAKLQELSGPMAETLRRLGETAGTGLDYTALQKV 358
            .|:.:.:..|.::..:::..:.:.:.|...:..:.|...|.:....|..:.|.|
Frog   396 GGILVVALPITIIFNKFSHFYRRQKALENAVRNSDRIPREDSNVSEDKNSEQSV 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	9/56 (16%)
		Ion_trans	<240..314	CDD:278921	26/82 (32%)
		Ion_trans_2	<266..319	CDD:285168	17/56 (30%)
kcns1	XP_002938059.3	BTB_POZ_KCNS1	18..123	CDD:349733
kcns1	XP_002938059.3	Ion_trans	185..420	CDD:395416	58/286 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000