Protein Alignment Sk1 and SPHK1

DIOPT Version :10

• Sequence 1: NP_572717.1
• Gene: Sk1 / 32089
• FlyBaseID: FBgn0030300
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_193885.6
• Gene: SPHK1 / 828239
• AraportID: AT4G21540
• Length: 485
• Species: Arabidopsis thaliana
• Alignment Length: 608
• Identity: 153/608 - (25%)
• Similarity: 251/608 - (41%)
• Gaps: 165/608 - (27%)

  Fly    68 RRETEEDDHINEQLIRIDDIIGSRYGRRLKKRARGGLNSC---RNPNVPGQEADSEPDSDNSAYL 129
            |:...|:|.:....|..|.::.:.....|...|.|.|.|.   |..:...:|..|.....|..
plant     3 RQPERENDELPSPAIISDRVLVNGVVTPLTLTAEGELRSTESGRRKSTLAKEILSFVVEGNKV-- 65

  Fly   130 YIYAYLKKEKPLRRVQTL-----RILRFRSSNDYGVN--------LQTAEMWHHTIRKHKRGNGS 181
                         ||:||     .|....|:.||..|        .::.::|.....:|....|.
plant    66 -------------RVKTLVEKGGGICCRGSAGDYARNDFVFEPLSDESRKLWSDKFHQHLVSLGR 117

  Fly   182 SSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTRRDLLT 246
            .      |:||:.:||..|....|::||::|.||..:|.:|.::|.|.:..:|||.||:..  ::
plant   118 P------KKLLVFVNPFGGKKTARKIFQEEVKPLFEDANIQLEIQETKYQLHAKEIVRSMD--VS 174

  Fly   247 RYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCNEPYE-PKPI 310
            :|.|||..||||:..||:|||:||.||:.|.: ||:|::|.|||||:.||:.    ||.. |...
plant   175 KYDGIVCVSGDGILVEVVNGLLEREDWKTAIK-LPIGMVPAGSGNGMIKSLL----EPVGLPCSA 234

  Fly   311 LHATLTCMAGKSTPMDVVRVELATRDKHFVMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAI 375
            ..||::.:.|::..:||..:...|..    .:|.|.:.|||:||||||||:.|.:|:.||.::.:
plant   235 TSATISIIRGRTRSLDVATISQGTTK----FFSVLMLAWGLVADIDIESEKFRWMGSARFDIYGL 295

  Fly   376 KRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEFHDLPEEEEGEAVL 440
            :|:|.||.|.||:.::...|.:               :.|.|:|..::        :|..|
plant   296 QRIICLRQYHGRILFVPAPGFE---------------SYGQRASCSID--------KEPSG---- 333

  Fly   441 DGEQFADAISLDRSVYRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAERV 505
                                       |.:|..|.  ||..:
plant   334 ---------------------------SDKTLVYQ--GPDSK----------------------- 346

  Fly   506 PTGTIPPLQMPLLSSDGWICEDGDFVMVHAAYTTHLSSDVFFAPESRLDDGLIYLVIIRRGVSRH 570
                        |.:..|....|.||.|........:.:...||:::..||.:.|::: :...:.
plant   347 ------------LENLDWREMKGPFVSVWLHNVPWGAENTLAAPDAKFSDGFLDLIVM-KDCPKL 398

  Fly   571 QLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPSS------SDGILVVDGE------------ 617
            .||:.|..|:.|||:   :.|:...:..:||.:||.:      .:||:..|||
plant   399 ALLSLMTKLSDGTHV---QSPYASYLKVKAFVLEPGARIDEPDKEGIIDSDGEVLARGRKSYKCD 460

  Fly   618 ---RVEYGPIQAEVMPGLINVMT 637
               .:.|..:|..|..||..:.:
plant   461 QKALMSYDKLQISVDQGLATLFS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	122/454 (27%)
SPHK1	NP_193885.6	PLN02958	8..485	CDD:215517	152/603 (25%)