Protein Alignment Sk1 and Cerk

DIOPT Version :10

• Sequence 1: NP_572717.1
• Gene: Sk1 / 32089
• FlyBaseID: FBgn0030300
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_036015253.1
• Gene: Cerk / 223753
• MGIID: 2386052
• Length: 564
• Species: Mus musculus
• Alignment Length: 581
• Identity: 139/581 - (23%)
• Similarity: 216/581 - (37%)
• Gaps: 205/581 - (35%)

  Fly   110 PNVPGQEADS---------EPDSDNSAYLYIYAYLKKEKP----LRRVQTLRILRFRSS--NDYG 159
            |:.||.:|.|         |...|...:.....:.|.|.|    :.||:.:|..|::.:  ..:.
Mouse    42 PSAPGADARSVLVSEIIAVEEKDDCEKHASSGRWHKMENPFAFTVHRVKRVRHHRWKWARVTFWS 106

  Fly   160 VNLQTAEMWHHTIRKHKRGNG-----SSSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEA 219
            .:.|...:|..|:|      |     :|.|    |.||:.:||..|.|:|:.:::|.||||.|.|
Mouse   107 ADEQLCHLWLQTLR------GLLESLTSRP----KHLLVFINPFGGKGQGKRIYEKTVAPLFTLA 161

  Fly   220 EVQYDLQITTHPQYAKEFVRTRRDLLT-RYSGIVVASGDGLFYEVLNGLMERM--------DWRR 275
            .:..::.||.|...|||   |..::.| .|.|||...|||:|.|||:|::.|.        :..|
Mouse   162 SITTEIIITEHANQAKE---TLYEINTDSYDGIVCVGGDGMFSEVLHGVIGRTQQSAGIDPNHPR 223

  Fly   276 AC---RELPLGIIPCGS---------GNGLAKSVAHHCNEPYEPKPILHATLTCMAGKSTPMDVV 328
            |.   ..|.:||||.||         |...|::.|.|                .:.|.|..:||.
Mouse   224 AVLVPSTLRIGIIPAGSTDCVCYSTVGTNDAETSALH----------------IIIGDSLAIDVS 272

  Fly   329 RVELATRDKHF----VMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVS 389
            .|       |:    :.||...:|:|...|:..:||:.|.:|..|:....:|..:..:.|:|.:|
Mouse   273 SV-------HYHNTLLRYSVSLLGYGFYGDLIKDSEKKRWMGLVRYDFSGLKTFLSHQYYEGTLS 330

  Fly   390 YLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEF------HDLPEEEEGEAVLDGEQFADA 448
            :                |||:.|....|.:.|..||.|      ..|.|||
Mouse   331 F----------------LPAQHTVGSPRDNKPCRAGCFVCRQSKQQLEEEE-------------- 365

  Fly   449 ISLDRSVYRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAERVPTGTIPPL 513
                                 :.|.|.|                    .|||..|.
Mouse   366 ---------------------KKALYGL--------------------ENAEEMEE--------- 380

  Fly   514 QMPLLSSDGWICEDGDFVMVHAAYTTHLS-----SDVFFAPESRLDDGLIYLVIIRRGVSRHQLL 573
                     |....|.|:.::|   |::|     |....:|.:.|.||...|::||: .||...|
Mouse   381 ---------WQVTCGKFLAINA---TNMSCACPRSPGGLSPFAHLGDGSSDLILIRK-CSRFNFL 432

  Fly   574 NFML-NLNAGTHLPIGED----PFIKVVPCRAF-----RIEPSSSDGILVVDGERVEYGPI 624
            .|:: :.|.       ||    .|::|...:.|     .:|...:|.   .:.|:.::|.|
Mouse   433 RFLIRHTNQ-------EDQFDFTFVEVYRVKKFHFTSKHVEDEDNDS---KEQEKQKFGKI 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	116/478 (24%)
Cerk	XP_036015253.1	DAGK_cat	84..466	CDD:445337	124/517 (24%)