Protein Alignment GCS1 and mogs

DIOPT Version :10

• Sequence 1: NP_572707.4
• Gene: GCS1 / 32073
• FlyBaseID: FBgn0030289
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: XP_031751080.1
• Gene: mogs / 619362
• XenbaseID: XB-GENE-5911793
• Length: 822
• Species: Xenopus tropicalis
• Alignment Length: 838
• Identity: 376/838 - (44%)
• Similarity: 507/838 - (60%)
• Gaps: 98/838 - (11%)

  Fly    61 MIGCVCLAI-ASYFGYLGYL-------------ETRVNTPFDHQKMVVHAGLEQPDRYWGSYRPL 111
            ::..|..|| .|.|.|.||:             ..||..|......:      .|:.:||||||.
 Frog    34 LVALVSCAIGVSAFAYSGYMRWSLALRVLTLHPSPRVWPPNSSSSAL------SPNMFWGSYRPQ 92

  Fly   112 TYFGMKTRDPHSLVMGLMWYTPSNLGPGGQGIRHWCEQGDKLDSYGWTHHDGRSFGVQEIQDLPF 176
            .|||||||.|||:|.||||.:.:    |...:||.|||||.|..|||..|||.:||||||.|..|
 Frog    93 LYFGMKTRSPHSVVTGLMWLSQA----GAPSLRHTCEQGDGLARYGWLLHDGENFGVQEITDRGF 153

  Fly   177 ELKTSFVKYPEGKQYGGDWTARISVR-NTTRAWDKSISLIWYVALDER--------TNGHIKYVS 232
            .|:|.|||.| |..:||||:.||... ..:.:..:.:||::|||.|.:        ...|:.:|:
 Frog   154 TLRTEFVKRP-GGDHGGDWSWRIRASPQASSSPGQILSLMFYVATDGQGTLTPHVAGRRHLTHVT 217

  Fly   233 DDKSPEPGVYGEAQGLGEFQVRFHAVKGKILHKS--YLSTVAPSLAKLKDTL-------FSHFRA 288
                      ||::.||.|.:||...:|...|.|  ||||..|.|..|.|.:       |:|...
 Frog   218 ----------GESEELGPFTLRFLTAEGGDGHVSYNYLSTTCPGLHTLTDVVRTSLRDHFTHPTE 272

  Fly   289 FADKRGN--RFIGL----PGEIVSQNGLPSSNPEPNFIAIQITAEVDFTLDITYQS--------- 338
            ....|||  |:.||    |..:  ..|.|:..|....:..|:|.::.|..::.::|
 Frog   273 SGGSRGNKRRYFGLDSYHPPPL--PPGTPAPPPHTQLVVHQLTLQLPFQAEVLFESGSFQQRPGQ 335

  Fly   339 TSGFSLGESIPKPPTGRAYQDSLQAKIAQFEQRFEDRFQLKQKGHSPEEVRFARNALSNLLGGIG 403
            .||.|||..:.:..|             ..|.||:..|:|::||.:|::|.||:.||||:|||:|
 Frog   336 LSGVSLGTELDRHKT-------------NMENRFQSIFRLEEKGFTPDQVAFAQAALSNMLGGMG 387

  Fly   404 YFYGSSRVQSVYTKNPVPYWKAPLYTAVPSRSFFPRGFLWDEGFHGLLISAWDIDIELDIICHWF 468
            ||||||.|:|.:...||.|..||||||||||||||||||||||||.|||..|:..:....:.||.
 Frog   388 YFYGSSVVKSPHNAEPVLYPAAPLYTAVPSRSFFPRGFLWDEGFHLLLIGRWNPSLAWQSLGHWL 452

  Fly   469 DLLNVEGWIPREQILGVEALAKVPEEFVTQRNSNANPPTFFLTLKKLLTSHRAELSQNGRLATLE 533
            ||:|.:||||||||||.||.:|||:|||.|::.||||||.||.|::||.:...:       ..|.
 Frog   453 DLMNADGWIPREQILGSEARSKVPDEFVIQKSENANPPTLFLALRQLLANTEGD-------EALR 510

  Fly   534 RLYPRVQAWFNWFNTTQRGEVLGTYLWRGRNATTTRELNPKSLSSGLDDYPRASHPTDKERHLDL 598
            |.:||:|.|::|:|:||.|.:..||.||||:....|.||||:|:||||||||||||:::|||:||
 Frog   511 RAWPRLQTWYDWYNSTQAGLLPHTYRWRGRDQDPLRFLNPKTLTSGLDDYPRASHPSEEERHVDL 575

  Fly   599 RCWIALAAGVMAELSTLLGKDDAKYYETASYLTDNVRLNRLHLAPYSEQYADWGLHTDQVKLK-- 661
            |||:|||:.|||:::..|.:|..:|....:.||||..|:..|.:.....|||:|.||....|:
 Frog   576 RCWMALASQVMADIAERLEEDGGRYRHDHNILTDNALLDHHHWSERLGAYADYGNHTQNTALEWV 640

  Fly   662 RPPSMAPQQQQRHHHQHYQLPEMQRVTGELPTYQFVDSAFGYVSLFPLLLEQLDHDSPYLTKLLN 726
            ||.: ||.|..|    ....|::.||..:.|..|:| .|.|||||||.||:.||..:|:|.:||:
 Frog   641 RPRA-APGQDPR----SVPPPQLIRVVRKPPRLQYV-GALGYVSLFPFLLQVLDPSAPHLGRLLD 699

  Fly   727 DLRDPEQLWTNYGLRSLSKRSPLYMQRNTEHDPPYWRGPIWININYLAAKALHHYGKIDGPNAAL 791
            .:||.::|||.||:|||||.||||:|||||||.||||||||||:|||..:||:.|.:::||:...
 Frog   700 LIRDADKLWTPYGIRSLSKGSPLYLQRNTEHDAPYWRGPIWINMNYLTVRALYLYSQMEGPHRDR 764

  Fly   792 ARQIYAELRDNLVGNILRQYKRSGYLWEQYDDTSGEGKGCNPFTGWTATVVLLMAEQF 849
            ...:|.|||.||:.|:.||||.:|:|||||:|.:|:|:||.|||||::.:||:|||::
 Frog   765 LVSLYRELRQNLLANLYRQYKNTGFLWEQYNDQTGQGQGCFPFTGWSSLLVLIMAEEY 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCS1	NP_572707.4	Glyco_hydro_63N	104..>256	CDD:465316	71/160 (44%)
		Glyco_hydro_63	352..847	CDD:397353	258/496 (52%)
mogs	XP_031751080.1	Glyco_hydro_63N	84..>246	CDD:465316	76/176 (43%)
		Glyco_hydro_63	336..820	CDD:397353	263/509 (52%)