DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34348 and lpcat2

DIOPT Version :9

Sequence 1:	NP_001096954.1	Gene:	CG34348 / 32072	FlyBaseID:	FBgn0085377	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001018492.1	Gene:	lpcat2 / 553683	ZFINID:	ZDB-GENE-050522-229	Length:	529	Species:	Danio rerio

Alignment Length:	265	Identity:	58/265 - (21%)
Similarity:	97/265 - (36%)	Gaps:	63/265 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LHSLLSSYIDLDYSLWLYRFLTPLIVTFLLPLVFVALIYISFLVLFIYKLHRQVIMRAVQGDRNF 75
            :|.|..|..|:.....|...|.||...||| ||.:.:..:|.::.|...|  :.::..:.|.|.|
Zfish    26 VHDLSLSTADITKCFLLGIILVPLRAIFLL-LVLLVMWPVSVIITFGQSL--KGVVEPMTGWRRF 87

  Fly    76 WRVGRKIVAAIWDAHARIYH---GYEVI--GLENVPQEGPALIVYYHGAIPIDMYYLNSRM---L 132
              :.|:::..:    .|:|.   |::|:  |.:....|.|.|.|..|.:....:..:.|.:   :
Zfish    88 --LHRRVMTFL----GRMYFFGMGFKVVVKGKKASTLEAPILAVAPHSSFFDAIACIESGLPSTV 146

  Fly   133 LQRERLIYTIGDRFLFKLPGWGTISEAFHVSPGTVQSCVSILRDGNLLAISPGGVYEAQFGDHYY 197
            .:.|.|...|..|||            ..|.|..|.......|...::.|.    ..|:.|.|:.
Zfish   147 SRIESLEAPIFGRFL------------RCVQPVLVSRTDPDSRRNTIIEIE----RRAKSGGHWP 195

  Fly   198 ELLWRNRVGFAKVAIEAKAPIIP---CFTQNLREGFRQVGIFRTFFMRLYNKVRIPVYPIYGGFP 259
            ::|                 |.|   |..::....|:|.|..          ..:||.|:...:|
Zfish   196 QVL-----------------IFPEGTCTNRSCLITFKQGGFV----------PGVPVQPVLIRYP 233

  Fly   260 VKFRT 264
            .|..|
Zfish   234 NKLDT 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34348	NP_001096954.1	PlsC	47..271	CDD:223282	45/229 (20%)
CG34348	NP_001096954.1	LPLAT_MGAT-like	90..298	CDD:153249	38/186 (20%)
lpcat2	NP_001018492.1	PlsC	49..297	CDD:223282	51/242 (21%)
		LPLAT_LPCAT1-like	98..309	CDD:153253	38/184 (21%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	128..133		1/4 (25%)
		EGTC motif	202..205		0/2 (0%)
		EFh	316..406	CDD:298682
		EFh	378..440	CDD:238008
		EF-hand_7	378..435	CDD:290234
		EF-hand_7	415..473	CDD:290234
		EFh	418..473	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900