DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt3 and rpt3

DIOPT Version :9

Sequence 1:	NP_001285108.1	Gene:	Rpt3 / 32047	FlyBaseID:	FBgn0028686	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_588437.1	Gene:	rpt3 / 2539539	PomBaseID:	SPCC576.10c	Length:	389	Species:	Schizosaccharomyces pombe

Alignment Length:	391	Identity:	291/391 - (74%)
Similarity:	340/391 - (86%)	Gaps:	5/391 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SSLDELDMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQFLE 89
            :|.:|:   |||.|:|.|::.||.:::||.:||::.::||:|.:.||||||||||||||||||||
pombe     2 NSTEEI---DLYNRWKALERQLEMLDLQEGFIKEDCKSLKRELIRAQEEVKRIQSVPLVIGQFLE 63

  Fly    90 AVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSISMLQPDEK 154
            |:||||.||||||||||.||||||:|||||||||||||.:|||||||:||||||||||||:|||:
pombe    64 AIDQNTAIVGSTTGSNYVVRILSTLDRELLKPSASVALQRHSNALVDILPPEADSSISMLRPDER 128

  Fly   155 PDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTT 219
            |||||||:||:|:||||:|||||||||..:||:|||||||||||:|||||.|||||.||||:.|.
pombe   129 PDVSYADVGGLDVQKQEVREAVELPLTQGDLYRQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTA 193

  Fly   220 ASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRIL 284
            |:||||||||||||||||||||||||||:|:||||||||||||||||||||||||||||||||||
pombe   194 ANFIRVVGSEFVQKYLGEGPRMVRDVFRMARENAPAIIFIDEIDAIATKRFDAQTGADREVQRIL 258

  Fly   285 LELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLVFSTITSKMN 348
            :|||.|||||||..||||||||||||||||||||||||||||||| ..||||:||||.|||:||.
pombe   259 IELLTQMDGFDQGANVKVIMATNRADTLDPALLRPGRLDRKIEFPSYRDRRQRRLVFQTITAKML 323

  Fly   349 LSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKNNIK-KDEQEHEFY 412
            ||.:|||:.|:.|||..|||.|.||.|:||:.|||::|.::|..|.|:.|...:| .|.::..||
pombe   324 LSPEVDLDTFIMRPDASSGAQIAAIMQDAGLLAVRKSRGVILQSDIEEAYARAVKPTDMEQFAFY 388

  Fly   413 K 413
            |
pombe   389 K 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3	NP_001285108.1	PTZ00454	22..413	CDD:240423	289/389 (74%)
Rpt3	NP_001285108.1	AAA	197..330	CDD:278434	120/133 (90%)
rpt3	NP_588437.1	PTZ00454	2..389	CDD:240423	289/389 (74%)
		P-loop_NTPase	99..>235	CDD:304359	113/135 (84%)
		AAA	171..303	CDD:278434	118/131 (90%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	240	1.000	Domainoid score	I452
eggNOG	1	0.900	-	-		E1_COG1222
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4744
Inparanoid	1	1.050	568	1.000	Inparanoid score	I180
OMA	1	1.010	-	-		QHG54142
OrthoFinder	1	1.000	-	-		FOG0004043
OrthoInspector	1	1.000	-	-		otm47076
orthoMCL	1	0.900	-	-		OOG6_101965
Panther	1	1.100	-	-	LDO	PTHR23073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1000
SonicParanoid	1	1.000	-	-		X2788
TreeFam	1	0.960	-	-
	14	13.860