Protein Alignment C901 and TNXB

DIOPT Version :10

• Sequence 1: NP_572673.1
• Gene: C901 / 32032
• FlyBaseID: FBgn0021742
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001415264.1
• Gene: TNXB / 7148
• HGNCID: 11976
• Length: 4491
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 106/317 - (33%)
• Similarity: 133/317 - (41%)
• Gaps: 72/317 - (22%)

  Fly    41 PLWKQRACEKSQKQR---QNAHYVCDEKGDFKCLPGWQGDLCQVPMCRRGCDPMNGYCQRPGECR 102
            |...||:|.:...||   :....|||        ||:.||.|.:..|.|||. ..|.|:. |.|.
Human   242 PDCSQRSCPRGCSQRGRCEGGRCVCD--------PGYTGDDCGMRSCPRGCS-QRGRCEN-GRCV 296

  Fly   103 CRIGYSGELC-----------------DKCIPLPG--------------CQHGGCTKPFECICKP 136
            |..||:||.|                 .:|:..||              |..||......|:|.|
Human   297 CNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWP 361

  Fly   137 GWAGLFCTEPSCRTGCHSTRGYCEAPGECRCRIGYAGRTCSECATMPG-C-QHGTCNKPLECLCL 199
            |:.|..|:..:|...|.. ||.|| .|||.|..||:|..|. ..:.|| | |.|.|... .|:|.
Human   362 GYTGEDCSTRTCPRDCRG-RGRCE-DGECICDTGYSGDDCG-VRSCPGDCNQRGRCEDG-RCVCW 422

  Fly   200 PGYTGLLCQTPICDPDCSKQHGYCRKPGECRCKVGWTGSQCD--KCFPYPG-C-ANGDCEAPWEC 260
            |||||..|.:..|..|| :..|.|.. |.|.|..|::|..|.  .|   || | ..|.||: ..|
Human   423 PGYTGTDCGSRACPRDC-RGRGRCEN-GVCVCNAGYSGEDCGVRSC---PGDCRGRGRCES-GRC 481

  Fly   261 NCHPGWGGMLCDEKLTYCVEHPDTCENGGKCTSLSREDGSYQCQCRQGFLGKNCEIR 317
            .|.||:.|..|..:.  |   |..|...|:|.     ||  :|.|..||.|::|..|
Human   482 MCWPGYTGRDCGTRA--C---PGDCRGRGRCV-----DG--RCVCNPGFTGEDCGSR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C901	NP_572673.1	DSL	<56..82	CDD:473190	8/25 (32%)
		EGF_CA	280..315	CDD:238011	11/34 (32%)
TNXB	NP_001415264.1	C_rich_MXAN6577	<191..295	CDD:469225	21/62 (34%)
		EGF_Tenascin	249..275	CDD:480934	10/33 (30%)
		PTZ00214	<254..669	CDD:173479	102/305 (33%)
		EGF_Tenascin	311..337	CDD:480934	3/25 (12%)
		C_rich_MXAN6577	314..418	CDD:469225	32/107 (30%)
		EGF_Tenascin	373..399	CDD:480934	13/27 (48%)
		EGF_Tenascin	559..585	CDD:480934
		EGF_Tenascin	719..745	CDD:480934
		fn3	762..831	CDD:394996
		fn3	843..919	CDD:394996
		fn3	1114..1161	CDD:394996
		fn3	1308..1388	CDD:394996
		FN3	1403..1485	CDD:238020
		fn3	1512..1589	CDD:394996
		fn3	1623..1693	CDD:394996
		FN3	<1673..2048	CDD:442628
		FN3	2020..2109	CDD:238020
		fn3	2132..2202	CDD:394996
		fn3	2235..2308	CDD:394996
		fn3	2346..2416	CDD:394996
		fn3	2445..2515	CDD:394996
		fn3	2551..2624	CDD:394996
		FN3	<2665..>2895	CDD:442628
		fn3	2773..2843	CDD:394996
		fn3	2876..2956	CDD:394996
		fn3	2990..3057	CDD:394996
		fn3	3092..3172	CDD:394996
		fn3	3206..3273	CDD:394996
		fn3	3308..3381	CDD:394996
		FN3	3384..>3762	CDD:442628
		fn3	3809..3884	CDD:394996
		fn3	3903..3985	CDD:394996
		fn3	4005..4083	CDD:394996
		FN3	<4061..>4251	CDD:442628
		fn3	4182..4259	CDD:394996
		Fibrinogen_C	4273..4482	CDD:395095