Protein Alignment C901 and DLK2

DIOPT Version :10

• Sequence 1: NP_572673.1
• Gene: C901 / 32032
• FlyBaseID: FBgn0021742
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_005249365.1
• Gene: DLK2 / 65989
• HGNCID: 21113
• Length: 476
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 101/342 - (29%)
• Similarity: 138/342 - (40%)
• Gaps: 94/342 - (27%)

  Fly    59 HYVCDEKGDFKCLPGWQGDLCQVPMCRRGCDPMNGYCQRPGECRCRIGYSGELCDKCIPLPGCQH 123
            |.||     ..|:.|..|...:...|...||..:|.|...|.|||..|:.|..|::|:.:|||||
Human   102 HLVC-----LLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQH 161

  Fly   124 GGCTKPFECICKPGWAGLFC--TEPSCRTGCHSTRGYCEAPGECRCRIGYAGRTCSECATMPGCQ 186
            |.|.:|::|||..||||.||  .|..|     :|:..|:..|:|.    |.|          |.:
Human   162 GTCHQPWQCICHSGWAGKFCDKDEHIC-----TTQSPCQNGGQCM----YDG----------GGE 207

  Fly   187 HGTCNKPLECLCLPGYTGLLCQTPICDPDCSKQHGYCRKPGE-------------------CRCK 232
            :       .|:||||:.|         .||.::.|.|.:.|.                   |||.
Human   208 Y-------HCVCLPGFHG---------RDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCL 256

  Fly   233 VGWTGSQC----DKCFPYPGCANG----DCEAPWECNCHPGWGGMLCDEKLTYCVEHPDTCENGG 289
            ||:.|::|    |.|...| ||||    |....:.|.|..|:.|..|...|..|...|  |:.|.
Human   257 VGFVGARCEVNVDDCLMRP-CANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRP--CQRGA 318

  Fly   290 KCTSLSREDGSYQCQCRQGFLGKNCEIRDDFLLTSEAPPRI--TPPTPAELVLELDGELDQNGQQ 352
            :|.....:   :.|.|..|:.||.||:    :|....||..  ||..|...|:
Human   319 RCRDRVHD---FDCLCPSGYGGKTCEL----VLPVPDPPTTVDTPLGPTSAVV------------ 364

  Fly   353 DIGAGVPDDSEPGGGLV 369
             :.|..|.....|.||:
Human   365 -VPATGPAPHSAGAGLL 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C901	NP_572673.1	DSL	<56..82	CDD:473190	6/22 (27%)
		EGF_CA	280..315	CDD:238011	9/34 (26%)
DLK2	XP_005249365.1	EGF_CA	182..222	CDD:238011	16/74 (22%)
		EGF_CA	267..303	CDD:238011	12/36 (33%)
		EGF_CA	305..341	CDD:238011	11/40 (28%)