Protein Alignment C901 and npnt

DIOPT Version :10

• Sequence 1: NP_572673.1
• Gene: C901 / 32032
• FlyBaseID: FBgn0021742
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_012810956.1
• Gene: npnt / 100488614
• XenbaseID: XB-GENE-952278
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 606
• Identity: 132/606 - (21%)
• Similarity: 182/606 - (30%)
• Gaps: 217/606 - (35%)

  Fly    61 VCDEKGDFKCLPGWQGDLCQVPMCRRG---CDPMNGYC--QRPGECRCRIGYSGELCDKCIPLPG 120
            :|.......|..||         .|:.   |.|.. |.  ||....|||   |..:|.     |.
 Frog    35 LCRYGNRIDCCWGW---------ARQSWGQCQPFY-YVLRQRIASVRCR---SQAICQ-----PA 81

  Fly   121 CQHGGCTKPFECICKPGWAGLFCTE-------------------PSCRTGCHSTRGYCEAPGECR 166
            |:||.|..|.:|.|.||:.|..|.:                   |            .|||.
 Frog    82 CKHGDCVGPNKCKCHPGYTGKTCNQDDELLTTVPEWYHEVPFLYP------------VEAPA--- 131

  Fly   167 CRIGYAGRTCSECATMP-GCQHGTCNK--PLECLCLPGY---------TGLLCQTPICDPDCSKQ 219
              .|......:||...| .|::...|.  ..:|.||.||         ..|.|....|...|...
 Frog   132 --TGVPPGDLNECGLKPRPCKYRCMNTYGSYKCYCLNGYMLMPDGSCSNALTCSMANCQYGCDVV 194

  Fly   220 HGYCRKPGECRC-----KVGWTGSQC---DKCFPYPGCANGDCEAPWECNCHPGWGGMLCDEKLT 276
            .|..|    |||     ::|..|..|   |:      ||.|....|.:..|...:|..:|.....
 Frog   195 KGDVR----CRCPSPGLQLGPDGRTCVDVDE------CATGKVVCPRQRKCVNTFGSYICKCHEG 249

  Fly   277 YCVEHP---------DTCENGG-KCTSLSR---EDGSYQCQCRQGFLGKNCEIRDDFLLTSEAPP 328
            |.:.|.         |.|..|. :|:..:|   ..|||:|:|.:|:.|...|        ....|
 Frog   250 YDLIHAAGKYQCFDIDECYTGQYQCSQFARCYNTPGSYKCKCSEGYRGNGAE--------CSRIP 306

  Fly   329 RITPPTPAELVLELDGELDQNGQQDIGAGVPDDSEPGGGLVGEKLPAGNEPERRKNDTVANVATA 393
            |:.              :|.:|        |.:..||                  .|:..|:.
 Frog   307 RVM--------------IDPSG--------PHNFLPG------------------KDSTRNII-- 329

  Fly   394 GTGAGAGPMNSLPGNSNATRTTLVVATETGSDNATNEALSAVTTRRATPIPLTSGEKTVKGNATS 458
                 .|..::|.|:..::..   :....|.|.....:.|.:|   |.|.|.|:.:.|.:.....
 Frog   330 -----RGNSSNLSGSEGSSNR---IPDLIGRDPKRPPSPSYIT---AKPAPKTTAKPTTRPLPKP 383

  Fly   459 VS-----VATGPQPR-----PPLPIVASQEQTIANLAPAGTVTVTATTAP--------------- 498
            |:     ..|.|.|:     ||.|......|.:....||.|....|||.|
 Frog   384 VTRPAPKPVTRPAPKPETRPPPQPTTRILTQPVTRPPPATTRPPPATTRPPQPAVTRPPPPVVTR 448

  Fly   499 ------------TATTAATSVTS------HKDKP--NVADEEEDEDDDDDEEDEDG--------- 534
                        |.|..|..||.      |...|  |....|.::...|......|
 Frog   449 PAPRPSTSPAIKTTTRPALVVTKEPEIALHTTVPVDNRIKVEPEKPRGDVFIPRQGVQHNLFDIF 513

  Fly   535 EYDEEEDEDEDDEEDDSDQLI 555
            |.::....||.:|.||...||
 Frog   514 EVEKGLSADEYEENDDPGVLI 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C901	NP_572673.1	DSL	<56..82	CDD:473190	4/20 (20%)
		EGF_CA	280..315	CDD:238011	13/47 (28%)
npnt	XP_012810956.1	FXa_inhibition	142..176	CDD:464251	9/33 (27%)
		cEGF	199..221	CDD:463661	7/25 (28%)
		EGF_CA	218..249	CDD:429571	8/36 (22%)
		EGF_3	267..302	CDD:463759	12/42 (29%)
		PHA03247	<306..473	CDD:223021	41/219 (19%)
		PRK11633	<353..>409	CDD:236940	15/58 (26%)
		MAM	537..677	CDD:99706