Protein Alignment CG2186 and rbm33

DIOPT Version :10

• Sequence 1: NP_001368978.1
• Gene: CG2186 / 32017
• FlyBaseID: FBgn0030243
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_001017336.2
• Gene: rbm33 / 550090
• XenbaseID: XB-GENE-492091
• Length: 1316
• Species: Xenopus tropicalis
• Alignment Length: 1424
• Identity: 300/1424 - (21%)
• Similarity: 471/1424 - (33%)
• Gaps: 458/1424 - (32%)

  Fly     6 DDLLNYELGDDIDDQALLGADEDELLLSDEELEKDVTSEVKQQMRAEAEEWAQEQIRQHERKHKE 70
            ||..:.||.||:.::.:|...:..|.||||||..|:       ::::.||
 Frog    28 DDDWDSELEDDLLEEDVLPGKKSSLDLSDEELNDDL-------LQSDEEE--------------- 70

  Fly    71 QLQADATAATEVTVAATATA------EVAPTLRAQPELASSPAPDPVPAKPLVAQVEKHVDTAH- 128
              |....:|..||::..|||      |::.::...||:..   |:....:.:..:||:....|.
 Frog    71 --QDPNYSAQGVTLSLNATAGGLTSFELSKSINEDPEVEE---PEMGEDEAVYEEVEEPEGCAED 130

  Fly   129 AAVAAEPAKEL---------------------------------VSASRSESPQQQAKEEAPPAD 160
            .|.|.|.|.||                                 ....:.:...|:|:..|...:
 Frog   131 FADAYEEADELPEEHTEYMDEETTDEVLDLEINEPLDEFQEEVYTQTYKRQKMMQEAEFAANDVE 195

  Fly   161 CAEKEATQNNGNSEEQAENAGSQSEAERGLGLCSLLASSQESLPSASSASVISDPREDDEEREER 225
            ..|:||.:.......:.::..:.||        .:...|||.:|....   .||..:|:||...|
 Frog   196 ETEEEAIEETAEESIETQDPANDSE--------EVPVESQEMVPETKE---YSDEDDDEEEGGGR 249

  Fly   226 TNYKTA-----------SERSDNNLRQQQE-----HAHMSPYQHQQRRLHGH--GDKPRVGGGGR 272
            ..:|:.           |.|...|:.:..|     .|.:..::..:|...|.  ..:.|.||...
 Frog   250 IRFKSERKEGTIIRLSDSTRERRNIPETLELSAEAKASLQEFEEMERMRKGRYCAKRGRRGGMNP 314

  Fly   273 FMHGQQQQQ------QQQQSQMGKPPRGIGTRHHL--------LRNPSPSFGIQQQRMGMAGMQP 323
            ...|:|:..      ::|:|..|:|.|.:..::.:        .||||..          :...|
 Frog   315 MFRGEQRHDSNDRRIREQRSSHGQPIRSLFHQNQIQPLLPMPRSRNPSSD----------SMTSP 369

  Fly   324 PPQR----YGMPGNAPPPQHLALMSTP-------VGAAPTAACLLPLTVPVTPLTLSIPQAHPSH 377
            |||.    .|.|          |||||       :........:.|:.||:.|
 Frog   370 PPQEKQRMVGKP----------LMSTPQQPKNIHINPHFKGNVVAPVQVPLLP------------ 412

  Fly   378 QVHQQQQQTLSNPTF----------IPIPGQY---PATQPPNQSPQQAPTNTQQPHSAPASPLHT 429
             ...|.:..:.:|.|          .|:||.:   |..|.|.::|...|.........|..|
 Frog   413 -APNQSRPPMGSPRFPGMPDFQHVPSPVPGNFNPPPRLQEPWRNPPPQPERETFFLGEPRFP--- 473

  Fly   430 PTHSHMMHHSHNPNG---GVL--HHLLP----HPHEQVRVGLLQPPPLAY-------------AP 472
              :.|:..|.:.|.|   .:|  :|.||    ||..|...|..||.|...             .|
 Frog   474 --NQHLFDHRNPPPGPPPPLLNNNHSLPNQGQHPFNQPGPGFNQPSPQPRFNQPGPQPNFSQPGP 536

  Fly   473 NPG-------------------GYRNGALLGPGPGPGLHQQHQSPHQQQSGMRP----PLYRNAP 514
            .||                   |:.......|||.||.:|....|...|||.:|    |.:....
 Frog   537 QPGFPQPGPGPQQNFNQPGPPPGFNQPGFSQPGPQPGFNQPGPQPGFTQSGPQPVFNQPGFGQPG 601

  Fly   515 PSYGYDQ-GHPPQHPQQFMRPHNGWRPQGDNARMQRPPLQTLPPHMMPGAPPNYANGMGMRGPPP 578
            |..|::| ||.|...||      |....|.|    :||.....|...|.||          |||.
 Frog   602 PQPGFNQVGHQPGFNQQ------GMNQPGYN----QPPNVGPQPAFNPPAP----------GPPG 646

  Fly   579 QQQQSQQPPQQQPAPQQAGNPLQQAVNPGQPPQQPNG--------------PPQQQ-----GSSS 624
            ..||.   |..|||..|:|...::.|.|..|...|.|              ||:.|     |...
 Frog   647 FNQQG---PLPQPAFNQSGFSRERPVRPNAPSPGPMGIPPFNQSSPNRHFPPPRPQFPPGPGQPF 708

  Fly   625 VPRVSKVLINPNFKGGVEAATNKFIKETHFMPAINSEAELLRQQVEFINKNRQYIEKRRMERS-- 687
            :|.     |.||.:|.::|.... ..:.|..|........:.||     ..||:::..:|..:
 Frog   709 MPH-----IQPNIQGPMQAPMQP-PHQPHHTPGPLKPPMPIPQQ-----PFRQHLQSPQMPLNNR 762

  Fly   688 --PPSSGSSTGAASSGQAGERRRTRSR-SRSRGRSYSPVKRVERERERERERERDRERDRERDRE 749
              ||.........:....|.::...:| |..|....:|
 Frog   763 LRPPKPRQGVPPQNMTMGGNQQMMHTRNSNLRELPIAP--------------------------- 800

  Fly   750 RYGANRAAGNRGFRRASSRDRDENRGAASTASAQGAGGSASSGAAPPKRRRSGSAGGGTARNPFS 814
                           |||.||::.: ..|.|..:..|.:|      |:.|..|      ..||..
 Frog   801 ---------------ASSLDRNKMK-PNSAAQMKPVGTTA------PQTRPVG------VGNPHV 837

  Fly   815 GEPRG---RPSETGSRSMPSDEDEETRNYRLEIEKQKQLREKIMRDKELKRRRAA---------- 866
            .:...   :..|...|....|||||||||||:||:||:|||.|::.|||:|::.|
 Frog   838 AKQANASIQMQEEVKREQFPDEDEETRNYRLKIEEQKRLREAILKQKELRRQQQAGARKKELLER 902

  Fly   867 -------------EEKLHEEKRAEQH---------------------NTSPARDDQEVAAGQGSA 897
                         :::|.::::.:|.                     ..:||..:::.:....:.
 Frog   903 LSHQQQQQQQQQQQQQLQQQQQQQQQQQQQQQQQQQQQVQQQTPPGPQQAPAEQEKKTSPVTNNV 967

  Fly   898 APTPA--ASKHRP-------TASAGERKVISLKRRDDQDASSVRSRQAQGS---------QSNAQ 944
            .|.|:  .::.||       |...|...|..|::......::..|...||.         |:...
 Frog   968 NPIPSLTGTQIRPNVKNRLLTQKPGTPPVNVLQKIPTVQHTTGASTPVQGQPKKIIKKTVQNRVM 1032

  Fly   945 AGQGQQQQQAARKQLTAAKIAPEAKRSITDHLAPSSKQHHHHHQQHHQTAAAPA---RTVVLGSG 1006
            .....|:....|..:.||::.|:....:..            .|...|.||.||   |||:..|.
 Frog  1033 TDNPVQKVHQVRPAVNAAQLGPQQIAKVAS------------VQGQPQAAARPAATKRTVMQRSN 1085

  Fly  1007 AVAG---GTPPKPRDKLRLGTPSDDEVELDYDDDDLLLDEEDRLLATPSPPPQ------------ 1056
            :.:|   .||.|.| .::|.....|...:..:.:..:...:.::.....||.|
 Frog  1086 SASGEAANTPTKVR-VIKLSAAGGDNANVSAEGNLPVQSLQPKINPQQRPPFQQRLQQQQLQQQQ 1149

  Fly  1057 -----KASSKRSATPEPLVVKRNHKAMRGGSSTSAPSFSSNQRRVVLKPTSNG---SSSSGGDQQ 1113
                 |.:..:....:|......|         ..|.|..:.|::...|.|.|   .:|..|..|
 Frog  1150 QRPIRKVTIAKGTVQQPPQQNLYH---------GPPPFQGHARQIRSHPESAGPRIMNSVQGHHQ 1205

  Fly  1114 QLSHSGRQRDRRRGGE---DSALQRKGGVG-----------SVGGSSSSGSGGGIFDRL 1158
            ......|.|.|..||:   ...:..|..:.           ||.|.|||.:.|.:.:.|
 Frog  1206 PNKVIMRGRGRGVGGQMGRGRMMPNKQNLRVVECKPQPCAVSVEGLSSSTTDGQLRNML 1264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2186	NP_001368978.1	PHA03247	<323..629	CDD:223021	97/394 (25%)
rbm33	NP_001017336.2	PTZ00341	<58..>172	CDD:173534	25/140 (18%)
		PHA03247	<351..773	CDD:223021	115/493 (23%)
		TPH	<846..>901	CDD:464007	26/54 (48%)
		RRM_SF	1246..1312	CDD:409669	8/19 (42%)