DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA4 and zen2

DIOPT Version :10

Sequence 1:NP_002132.3 Gene:HOXA4 / 3201 HGNCID:5105 Length:320 Species:Homo sapiens
Sequence 2:NP_476794.1 Gene:zen2 / 40827 FlyBaseID:FBgn0004054 Length:252 Species:Drosophila melanogaster


Alignment Length:81 Identity:42/81 - (51%)
Similarity:59/81 - (72%) Gaps:1/81 - (1%)


- Green bases have known domain annotations that are detailed below.


Human   193 VVYPWMK-KIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSE 256
            ::||.:: .:..:....:.:..:.||||||::..|::|||:|||.|:||.|.|||||:..|.|:|
  Fly    20 MMYPCVELNVEAAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTE 84

Human   257 RQVKIWFQNRRMKWKK 272
            |||||||||||||.||
  Fly    85 RQVKIWFQNRRMKLKK 100

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA4NP_002132.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 19..77
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 101..168
Antp-type hexapeptide 194..199 2/4 (50%)
Homeodomain 216..272 CDD:459649 38/55 (69%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 273..320 42/81 (52%)
zen2NP_476794.1 Homeodomain 44..100 CDD:459649 38/55 (69%)
Blue background indicates that the domain is not in the aligned region.

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