DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG2889 and PRDM5

Sequence 1:NP_001245615.1 Gene:CG2889 FlyBaseID:FBgn0030206 Length:581 Species:Drosophila melanogaster
Sequence 2:XP_011529864.1 Gene:PRDM5 HGNCID:9349 Length:641 Species:Homo sapiens

Alignment Length:407 Identity:99/408 (24%)
Similarity:151/408 (37%) Gaps:82/408 (20%)


  Fly   232 DQRTTTESQESELQAVLERKPKGCSRAQLAKSYEKAIASYMSASCDLCEFSAPYLSE--LKTHFL 294
            |.....|.:|.::..|::......||.|.....:..:......:|..||.|  :.||  |..|..
Human   125 DSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDRLGCKEDYACPQCESS--FTSEDILAEHLQ 187

  Fly   295 EVHQ-----REYYIKCCGKVFTRASKLMDHIRK-------HINPKLFTCTICK------------ 335
            .:||     :|:..|.|||.|.....|..|:.:       ..:.:.|.|::|.            
Human   188 TLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQCTAKSSLKESSRSFQCSVCNSSFSSASSFEQH 252

  Fly   336 ------------------KSLNSQDYLATHIETVH-------------NKVAQIGKVLK------ 363
                              |.|.|:|.|..|.|.||             ||.......|:      
Human   253 QETCRGDARFVCKADSCGKRLKSKDALKRHQENVHTGDPKKKLICSVCNKKCSSASSLQEHRKIH 317

  Fly   364 --FPCPKCERTFSSERRMANHLAKHDTDQLE----------HTCEICCKSFANVHRLRRHIQSIH 416
              |.|.:|.:.|.|..::..|:..|...:|.          :.||||.|||..:.::..| :.||
Human   318 EIFDCQECMKKFISANQLKRHMITHSDMRLSPLIFLIEKRPYNCEICNKSFKRLDQVGAH-KVIH 381

  Fly   417 EDLHRHVCDICGKKFKFKPSFERHLLEHQGVVAPAVECPICRVWLKNEHSLRLHRFTHDSTDTV- 480
            .:...:.|.:|||.|..:..::.|...|.  .....:|..|:...:...||:.|...|:|..|. 
Human   382 SEDKPYKCKLCGKGFAHRNVYKNHKKTHS--EERPFQCEECKALFRTPFSLQRHLLIHNSERTFK 444

  Fly   481 CPHCGKTCTSRTALRGHVKYAHKLTTNLQCTFCEKTFKQQRNLDEHMAIHTGLQLYNCPHCPKEC 545
            |.||..|...:..|..||:..|:.....:|..|.|.|.....|..|...|||.:...||:|.::.
Human   445 CHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKICPYCGQKF 509

  Fly   546 RSRSNMYVHIKQRHADE 562
            .|...:.|||:. |..|
Human   510 ASSGTLRVHIRS-HTGE 525

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG2889NP_001245615.1 zf-AD 2..79 CDD:285071
C2H2 Zn finger 276..297 CDD:275368 8/23 (35%)
C2H2 Zn finger 306..323 CDD:275368 6/24 (25%)
C2H2 Zn finger 331..352 CDD:275368 10/51 (20%)
C2H2 Zn finger 366..386 CDD:275368 5/20 (25%)
C2H2 Zn finger 395..416 CDD:275368 9/21 (43%)
C2H2 Zn finger 424..444 CDD:275368 6/20 (30%)
C2H2 Zn finger 481..502 CDD:275368 7/21 (33%)
C2H2 Zn finger 510..530 CDD:275368 6/20 (30%)
C2H2 Zn finger 538..556 CDD:275368 7/18 (39%)
PRDM5XP_011529864.1 SET 20..123 CDD:279228
COG5048 <145..338 CDD:227381 41/195 (21%)
C2H2 Zn finger 169..190 CDD:275368 8/23 (35%)
C2H2 Zn finger 201..221 CDD:275368 7/20 (35%)
C2H2 Zn finger 236..256 CDD:275368 2/20 (10%)
COG5048 262..631 CDD:227381 71/269 (26%)
C2H2 Zn finger 264..287 CDD:275368 8/23 (35%)
C2H2 Zn finger 297..317 CDD:275368 3/20 (15%)
C2H2 Zn finger 322..342 CDD:275368 5/20 (25%)
C2H2 Zn finger 361..381 CDD:275368 9/21 (43%)
C2H2 Zn finger 389..409 CDD:275368 6/20 (30%)
C2H2 Zn finger 417..437 CDD:275368 5/20 (25%)
C2H2 Zn finger 445..462 CDD:275368 6/17 (35%)
C2H2 Zn finger 474..494 CDD:275368 6/20 (30%)
C2H2 Zn finger 502..522 CDD:275368 7/21 (33%)
zf-H2C2_2 515..538 CDD:290200 5/13 (38%)
C2H2 Zn finger 530..550 CDD:275368
zf-H2C2_2 543..567 CDD:290200
C2H2 Zn finger 558..578 CDD:275368
zf-H2C2_2 571..594 CDD:290200
C2H2 Zn finger 586..606 CDD:275368
C2H2 Zn finger 615..636 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 0.800 Consistency score
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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