Protein Alignment CG32683 and ARRB2

DIOPT Version :10

• Sequence 1: NP_727419.1
• Gene: CG32683 / 31970
• FlyBaseID: FBgn0052683
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: XP_011522160.1
• Gene: ARRB2 / 409
• HGNCID: 712
• Length: 440
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 133/534 - (24%)
• Similarity: 207/534 - (38%)
• Gaps: 197/534 - (36%)

  Fly   101 TQRVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDEE 165
            |:||:||:||||.||:||..|:.....:....:.|:|.|||..::..:|:..||..|||||||.:
Human    37 TRRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLD 101

  Fly   166 VMGLRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAK 230
            |:||.|..:..::.:|.:|.:..| |...:.||:.|:::||..||||..::....|.||.|.|..
Human   102 VLGLSFRKDLFIATYQAFPPVPNP-PRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGP 165

  Fly   231 RYYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQS 295
            ...|...|..:::|.|.|...:||.|:|.||::.:|.:             |:|
Human   166 EDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKV-------------QFA----------- 206

  Fly   296 PPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRSK 360
                                                                             
Human   207 ----------------------------------------------------------------- 206

  Fly   361 SEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVD--KPFLLHDGR 423
                  |..|                                     |||.|.:  :.||:.|..
Human   207 ------PEKP-------------------------------------GPQPSAETTRHFLMSDRS 228

  Fly   424 VGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNVTP 488
            :.|.|||||..|.|||.:.|.|::.|:|.|||:|::|...|:.|:|:|:..::|..||..:.
Human   229 LHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQ--- 290

  Fly   489 PVDRTVAAGASLNTTVTLRP--QRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQNA 551
              |..|:..::.....|:.|  .....|..:||:..|:     .|.|...:::.::.
Human   291 --DDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLK-----HEDTNLASSTIVKE-------- 340

  Fly   552 QLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLSGM 616
                                                   |.|:|  |..|.|||.|||||.:| .
Human   341 ---------------------------------------GANKE--VLGILVSYRVKVKLVVS-R 363

  Fly   617 GGELSLKLPFVLVH 630
            ||::|::|||||:|
Human   364 GGDVSVELPFVLMH 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32683	NP_727419.1	Arrestin_N	135..268	CDD:451447	49/132 (37%)
		Arrestin_C	421..632	CDD:214976	60/212 (28%)
ARRB2	XP_011522160.1	Arrestin_N	50..206	CDD:451447	55/169 (33%)
		Arrestin_C	225..380	CDD:214976	60/213 (28%)