Protein Alignment CG32683 and Arrb2

DIOPT Version :10

• Sequence 1: NP_727419.1
• Gene: CG32683 / 31970
• FlyBaseID: FBgn0052683
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001258287.1
• Gene: Arrb2 / 216869
• MGIID: 99474
• Length: 421
• Species: Mus musculus
• Alignment Length: 536
• Identity: 138/536 - (25%)
• Similarity: 208/536 - (38%)
• Gaps: 199/536 - (37%)

  Fly   100 GTQRVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDE 164
            || ||:||:||||.||:||..|:.....:....:.|:|.|||..::..:|:..||..|||||||.
Mouse     6 GT-RVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDL 69

  Fly   165 EVMGLRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPA 229
            :|:||.|..:..::.:|.:|.:..| |...:.||:.|:|:||..||||..::....|.||.|.|.
Mouse    70 DVLGLSFRKDLFIATYQAFPPMPNP-PRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPG 133

  Fly   230 KRYYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQ 294
            ....|...|..:::|.|.|...:||.|:|.||::.:|.:        ..|||
Mouse   134 PEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKV--------QFAPE------------- 177

  Fly   295 SPPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRS 359
                  ||
Mouse   178 ------TP--------------------------------------------------------- 179

  Fly   360 KSEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVD--KPFLLHDG 422
                                                            |||.|.:  :.||:.|.
Mouse   180 ------------------------------------------------GPQPSAETTRHFLMSDR 196

  Fly   423 R-VGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNV 486
            | :.|.|||||..|.|||.:.|.|::.|:|.|||:|:||...|:.|:|:|:..::|..||..:.
Mouse   197 RSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQ- 260

  Fly   487 TPPVDRTVAAGASLNTTVTLRP--QRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQ 549
                |..|:..::.....|:.|  .....|..:||:..|:     .|.|...:::.::.
Mouse   261 ----DDQVSPSSTFCKVYTITPLLSDNREKRGLALDGQLK-----HEDTNLASSTIVKE------ 310

  Fly   550 NAQLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLS 614
                                                     |.|:|  |..|.|||.|||||.:|
Mouse   311 -----------------------------------------GANKE--VLGILVSYRVKVKLVVS 332

  Fly   615 GMGGELSLKLPFVLVH 630
             .||::|::|||||:|
Mouse   333 -RGGDVSVELPFVLMH 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32683	NP_727419.1	Arrestin_N	135..268	CDD:451447	50/132 (38%)
		Arrestin_C	421..632	CDD:214976	62/213 (29%)
Arrb2	NP_001258287.1	Arrestin_N	19..175	CDD:451447	55/164 (34%)
		Arrestin_C	199..350	CDD:214976	60/209 (29%)