Protein Alignment CG32683 and Arr3

DIOPT Version :10

• Sequence 1: NP_727419.1
• Gene: CG32683 / 31970
• FlyBaseID: FBgn0052683
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: XP_006527925.1
• Gene: Arr3 / 170735
• MGIID: 2159617
• Length: 494
• Species: Mus musculus
• Alignment Length: 631
• Identity: 140/631 - (22%)
• Similarity: 224/631 - (35%)
• Gaps: 252/631 - (39%)

  Fly    91 DRSTHRDEFGTQRVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYR-VYAQLT 154
            |.|.|       ||:||||.|...::||..|:.....:....:.|:|.|||:.::|.: |:.:||
Mouse    43 DCSPH-------RVFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVVLVDPEYLEGRKSVFVRLT 100

  Fly   155 LTFRYGREDEEVMGLRFCNEAIMSLHQIWPRLEEPT--PESLSPLQEALMKRLGDGAHPFTLSLS 217
            ..|||||:|.:|:||.|..:..:...|:.|  .|||  ...|:.|||.|:.:||..|:||||.:.
Mouse   101 CAFRYGRDDLDVIGLTFRKDLYVQTKQVAP--AEPTSIQGPLTALQERLLHKLGVNAYPFTLQMV 163

  Fly   218 SYAPPSVQLVPAKRYYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQ 282
            :..|.||.|.|.....|.|.|..::|:.|.|:..:||..:..||::.||.:             |
Mouse   164 ANLPCSVTLQPGPEDSGKPCGVDFEVKSFCAENLEEKIPKSDSVQLVVRKV-------------Q 215

  Fly   283 YAAFAGRQNIAQSPPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSP 347
            ::|                                                           |.|
Mouse   216 FSA-----------------------------------------------------------LEP 221

  Fly   348 KSFRFSGRFGRSKSEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGS 412
                                                                    ||  ||...
Mouse   222 --------------------------------------------------------GP--GPSAQ 228

  Fly   413 VDKPFLLHDGRVGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFK 477
            ..:.|.|....:.|:|.:|:..:.|||.:.|.|:|.|.:.|.:|::::..:....|..::...::
Mouse   229 TIRSFFLSSQPLQLQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAGLSKYVVSSYHTRSYQ 293

  Fly   478 ---------------------NVVADSDNVTPPVDR------------TVAAGASLNTTVTLRPQ 509
                                 :||..:|.|...:|:            ||||.:|.:.|..:.|.
Mouse   294 RAVSWSHVGDQLIGHLLSLTFSVVQTTDVVLYSLDKYTKTVFVQEFTETVAANSSFSQTFAVTPL 358

  Fly   510 RGPT--KNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQNAQLLGGCGHPLGSPALVTPHPH 572
            ....  |..:||:..|:     .|.|. :|:|.|..|.   .|.:|||
Mouse   359 LAANCQKQGLALDGKLK-----HEDTN-LASSTILRPG---MNKELLG----------------- 397

  Fly   573 LWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLSG---MGG----ELSLKLPFVLVH 630
                                        |.|||.|:|.|.:|.   :||    ::.::||.:|:|
Mouse   398 ----------------------------ILVSYKVRVNLVVSYGGILGGLPASDVGVELPVILIH 434

  Fly   631 VDET--QRPGFAS-----ATLGELRMEMERLALHDAPVGKRNGRRQ 669
            ...:  :|.|.|:     |:.|..|.. |:..|      :|:..||
Mouse   435 PKPSPGERAGEATRNYYPASCGAKRFS-EQSGL------RRSDNRQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32683	NP_727419.1	Arrestin_N	135..268	CDD:451447	53/135 (39%)
		Arrestin_C	421..632	CDD:214976	53/252 (21%)
Arr3	XP_006527925.1	Arrestin_N	59..215	CDD:451447	56/170 (33%)
		Arrestin_C	236..437	CDD:214976	53/254 (21%)