Protein Alignment CG15306 and MAPRE3

DIOPT Version :10

• Sequence 1: NP_572618.1
• Gene: CG15306 / 31961
• FlyBaseID: FBgn0030191
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_036458.2
• Gene: MAPRE3 / 22924
• HGNCID: 6892
• Length: 281
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 85/301 - (28%)
• Similarity: 140/301 - (46%)
• Gaps: 66/301 - (21%)

  Fly     7 HNVTVTHNSLVQWSRGDILDWFNETLQCNLINIEQLCTGAAYCNLMHMLYPKLINLKRVKFFSNQ 71
            ::.:||..:|   ||.|:|.|.|::|..|...|||||:|||||..|.||:|..::|::|||.:..
Human     6 YSTSVTSENL---SRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKL 67

  Fly    72 EYEYVNNFKELQKAFNKVNVSLPAEVNDLIKGHRVENFKFAVWFRHFFNVNHT-KDKCAGYDALV 135
            |:||::|||.||.||.|:.|.....|..|:||...:||:|..||:.||:.|:. ||    |:.|:
Human    68 EHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKD----YNPLL 128

  Fly   136 ARDHQNIG---IGSSKLTTKDRFRLVKVKTTAIRGKVATCQATINSSLCTGKANQDEDSQHTD-- 195
            ||..|::.   ....::..|.:    |:..||:..:.:.          ||..|.....:.::
Human   129 ARQGQDVAPPPNPGDQIFNKSK----KLIGTAVPQRTSP----------TGPKNMQTSGRLSNVA 179

  Fly   196 -----KKDEDSRDQGSQYEDSP--GMDSQYKDC--------RDQDSQYEDSHGKDSQYKD----C 241
                 :|:..|...|....|:.  .::.|..|.        :::|..:       |:.:|    |
Human   180 PPCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYF-------SKLRDIELIC 237

  Fly   242 RDQGSQ------------YEDSHGMDSQYEDSRDQDSQYED 270
            ::..|:            |....|. :..||...::.|.||
Human   238 QEHESENSPVISGIIGILYATEEGF-APPEDDEIEEHQQED 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15306	NP_572618.1	CH	18..124	CDD:425596	50/105 (48%)
		MSCRAMM_ClfA	<185..346	CDD:468110	19/119 (16%)
MAPRE3	NP_036458.2	BIM1	16..279	CDD:227542	82/288 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..181		3/33 (9%)
		DCTN1-binding	217..281		12/69 (17%)
		APC-binding	217..260		6/49 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..281		6/18 (33%)