Protein Alignment Gip and HYI

DIOPT Version :9

• Sequence 1: NP_511106.1
• Gene: Gip / 31960
• FlyBaseID: FBgn0011770
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001317455.1
• Gene: HYI / 81888
• HGNCID: 26948
• Length: 302
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 96/291 - (32%)
• Similarity: 160/291 - (54%)
• Gaps: 42/291 - (14%)

  Fly     3 LKFAANLNFLFTERATSIAERIRLAHQNGFRAVEIPYPEGETSDVVS-AVKETGVVVSLVNL-AF 65
            |:|:|||::||.| .:.:..|:|.|..:||.|||:.:|..||.:.:: |.:|.|:.:.|:|. ..
Human     4 LRFSANLSWLFPE-LSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLINTPPG 67

  Fly    66 DKSDDQLRFGSTSVPGSEKLFRSQLDATIDFARQVNC--GK------------------------ 104
            |:...::..|  :|||.:..||..|:..:   |..:|  |:
Human    68 DQEKGEMGLG--AVPGRQAAFREGLEQAV---RSGHCLMGRKLSVPCKGAVARGGLVYLAAFLRL 127

  Fly   105 --IHLTAGLFKGGQE-----SDYTKTYTANLKIAADSLRASKMIGVIEPIN-KYAVPGYYMNSYS 161
              |||.||....|.:     ::....:..||:.||..|....::|::|||| :...|.|::::..
Human   128 DMIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQ 192

  Fly   162 KAAGILADVAADNIQLLADLYHLQHLHGNVSKTLEEYKALIGHFQIAQVPHRHEPDVSGELDYGF 226
            :||.||..|...|:||..|::|.|.:.||::..:.|:..::||.|:||||.|.||...|||::.:
Human   193 QAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPY 257

  Fly   227 VFKALQEFGYDGWIGCEYKPKTTTVEGLGWV 257
            :|:.|::.||.|::||||:|:..|||||.|:
Human   258 LFQLLEDEGYKGFVGCEYQPRGDTVEGLSWL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gip	NP_511106.1	OH-pyruv-isom	4..256	CDD:163190	94/287 (33%)
		AP_endonuc_2	24..222	CDD:279585	69/233 (30%)
HYI	NP_001317455.1	Hyi	3..291	CDD:226149	96/291 (33%)
		AP_endonuc_2	24..255	CDD:279585	71/235 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153086
Domainoid	1	1.000	114	1.000	Domainoid score	I6098
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12824
Inparanoid	1	1.050	180	1.000	Inparanoid score	I4011
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52228
OrthoDB	1	1.010	-	-		D1440394at2759
OrthoFinder	1	1.000	-	-		FOG0005694
OrthoInspector	1	1.000	-	-		oto88527
orthoMCL	1	0.900	-	-		OOG6_106707
Panther	1	1.100	-	-	LDO	PTHR43489
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6107
SonicParanoid	1	1.000	-	-		X4089
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.940