DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gip and C05D11.5

DIOPT Version :9

Sequence 1:	NP_511106.1	Gene:	Gip / 31960	FlyBaseID:	FBgn0011770	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_498404.1	Gene:	C05D11.5 / 182258	WormBaseID:	WBGene00015483	Length:	262	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	85/256 - (33%)
Similarity:	143/256 - (55%)	Gaps:	8/256 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KFAANLNFLFTERATSIAERIRLAHQNGFRAVEIPYPEGETSDVV-SAVKETGVVVSLVNLAFDK 67
            :.|||||.|||.  ..:.:|...|...||:.||:..|..|.::.: .|..|..:..:|:|.....
Worm     6 RVAANLNMLFTN--LPLLQRYGAAASAGFKLVEVSIPYTEPAEKLREAADEYHLKHTLINAPPGN 68

  Fly    68 SDDQLRFGSTSVPGSEKLFRSQLDATIDFARQVNCGKIHLTAGLFKGGQESDYT-KTYTANLKIA 131
            .||..| |..|:..::|.||..||..|::|:.:.|.::|:.||:.|...:.:.. :||:.|::.|
Worm    69 WDDGFR-GLASLKSAKKEFRKSLDTAIEYAKALGCCRVHVMAGIPKSDDDLENAHQTYSENVRFA 132

  Fly   132 ADSLRASKMIGVIEPINKYAVPGYYMNSYSKAAGILADVAADNIQLLADLYHLQHLHGNVSKTLE 196
            |:..:..|:|.:|||||||.:|||::|:|..|..::....::|:::..|.:|.|.::|.:...:.
Worm   133 AEKFKEHKLICLIEPINKYTIPGYHLNNYEDAMDVIQMDQSNNLKIQYDTFHAQQINGQIGAIMR 197

  Fly   197 EYKALIGHFQIAQVPHRHEPDVSGELDYGFVFKALQEFGYDGWIGCEY---KPKTTTVEGL 254
            :.|..||:.|:||||:|...|..||:||.|:|..::.......||.||   ||....:|.:
Worm   198 KLKDYIGYIQVAQVPNRGACDTRGEIDYHFIFDEIRSINPSWVIGAEYLDAKPSFNWIENM 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gip	NP_511106.1	OH-pyruv-isom	4..256	CDD:163190	85/256 (33%)
Gip	NP_511106.1	AP_endonuc_2	24..222	CDD:279585	64/199 (32%)
C05D11.5	NP_498404.1	Hyi	6..251	CDD:226149	83/247 (34%)
C05D11.5	NP_498404.1	AP_endonuc_2	26..224	CDD:279585	65/198 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162745
Domainoid	1	1.000	119	1.000	Domainoid score	I3603
eggNOG	1	0.900	-	-		E1_COG3622
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12824
Inparanoid	1	1.050	154	1.000	Inparanoid score	I2926
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52228
OrthoDB	1	1.010	-	-		D1440394at2759
OrthoFinder	1	1.000	-	-		FOG0005694
OrthoInspector	1	1.000	-	-		oto19021
orthoMCL	1	0.900	-	-		OOG6_106707
Panther	1	1.100	-	-	LDO	PTHR43489
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6107
SonicParanoid	1	1.000	-	-		X4089
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800