|
Fly 1 MYSEWASLSAQITANSCGAQCFSVLNKFPASAGREVVVSVVKQLGTNLGITQNAEPSHLVK-DEE 64
|||||.||...|.::.... |||:.:|.|.||||..:||:.||..||.:..|....|:| |:|
Mouse 1 MYSEWRSLHLVIQSDQGHT---SVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKE 62
Fly 65 VKWCMDVICFGLSLPLQEHETIKDCVNVYCEWLTALHPQPRISVPKPICEDANLYARQIINHFHN 129
|||.|:|||:||:||| :.||:|.||:||.:|:.|| ..|:.|:|.||.::.|||.:.|:.|..|
Mouse 63 VKWTMEVICYGLTLPL-DGETVKYCVDVYTDWIMAL-VLPKDSIPLPIIKEPNLYVQSILKHLQN 125
Fly 130 LFVPRQGEILPFLYQTTLGADTIKRQAVLCHRVLRTLQQTAQISQLMDRQTWDTLLLFLLAINEI 194
||||||.: |:..|: ||.:|||.:|:.|:.|.:|.|:||:.||||||.||:|
Mouse 126 LFVPRQEQ----------GSSQIR----LCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDI 176
Fly 195 LLAPPTVKDDVGDQLCERVLSVLFEVWLLACVRSFPSPSMWKTLQESCAMWRHRVALVDQWNRVN 259
|||||||:..:.:.|.|:::.||||||||||.|.||:|..|||.:|..|.|||..|:|:||::|.
Mouse 177 LLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVI 241
Fly 260 LALTARLLEFSYGPAFPQLKNADEDGQLIPIGMSNDCVAQTWYRFLRMIGNPTALCSPHIISKSS 324
.|||:|||.|:|||:||..|..|||..|||..|.|:|:||||:|||.|:.||..|.:|.:||.:.
Mouse 242 CALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTP 306
Fly 325 HFVQWALTHEKG--AETHQHPCLQQLPQIFLNAMKGISSQVDAFLGVYQPPPQQTDGVVTNLLEI 387
.| |....:..| .|..|:|||:.|||||..||:|||..||||||:.:|
Mouse 307 KF-QEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP--------------- 355
Fly 388 RHSLNEATSSTLQQFIHSSSATNIANQQNQPAHHHHHLHYPHLHLHGAGSFLRDNFMSNSASSAL 452
.|:||
Mouse 356 --------------------------------------------------------RSDSA---- 360
Fly 453 NAIMGHHGGHHGHHHQQQQQQQQQLQISASPTSSLTTSGSSAVGSTSAGGSHSAGVVGSISFGAT 517
..:|.:.|:...|:||.:
Mouse 361 ---------------------------PPTPVNRLSMPQSAAVNT-------------------- 378
Fly 518 ESPGPGQASASATPTPPLQRRLAKSFSVAPTITQQKGLSKTSLIGLTGGGARNAISSSSTTTTNA 582
|||..|| ...:|..|...|||.: ||.:.
Mouse 379 --------------TPPHNRR-------HRAVTVNKATMKTSTV----------------TTAHT 406
Fly 583 GSTGGTGSGDGSAPAPLPTTPTSTSGPPSASSSINSLPLTSMGAGVELAVARPKCNSILHVFHEW 647
... ....|:.:|| ::|..||..| ..|| |..|||.||||::|..|
Mouse 407 SKV----QHQASSTSPL-SSPNQTSSEP------RPLP----------APRRPKVNSILNLFGSW 450
Fly 648 LFEAA------HIGGDTWRQN-------------RKKQACEASKRPSSMIMEHRKGSISLSQPNS 693
||:|| |.|.: |.| :...|.:|| ||.|:....:|....
Mouse 451 LFDAAFVHCKLHNGIN--RDNSMTASFIQILLSYKSSIATQAS-------MEFRRKGSQMSTDTM 506
Fly 694 LNDP----QSLPPTLTIDKYESGRAEAIGTLCKIFCAKKTGEEILPVYLARFYMALQQCLKITES 754
:::| ...| |.||:|||||.||||:|||:|||||||||.||:||||.|.|.|:|.:
Mouse 507 VSNPVFDASEFP-----DNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQIND- 565
Fly 755 RECDETLASILLHSSDLFRLDLDGINVLLPGFIAALEIVLPDKDLKLKTQSMVFNRTELRRSAIN 819
..|...|||::|:|..||..||.||:|::|.||:|||.:|||::|. |.:|.| |.||||||:||
Mouse 566 YVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELS-KFKSYV-NPTELRRSSIN 628
Fly 820 ILLSIMVLPLHYQTLPIRDLTCE---------SSEKMFTFIQLKSRLMNILMNALQVETDAQNTH 875
||||::.||.|:.|:. .::..| |.:|..||:.||.||:|||:.|||.|||..||.
Mouse 629 ILLSLLPLPHHFGTVR-SEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQ 692
Fly 876 MLLGGLLLCVQDAVTFE----ETELGGGNANLSQNSSGVQHHDANLLSSACSERSASLVSAGTAS 936
|:||.:|..|||:...| :.|:|||..|| :|.|..::|.:|
Mouse 693 MILGAMLNIVQDSALLEAIGCQMEMGGGENNL---------------------KSHSRTNSGISS 736
Fly 937 LGGQTTATMGAGSGSIRDTASAHDYPSLTISDDMSFEFGQELEGVTTYDNAHALFVRATYLVCHR 1001
..| ||...|....:.|:..:..|.....|..| ....|:|..|.:|:.:||..|
Mouse 737 ASG----------GSTEPTTPDSERPAQALLRDYDVALGYIL--ALNTDSAAGLLIRSIHLVTQR 789
Fly 1002 LISSWKTDLNVSLAALELLSGLARLHIRETDALECKRAVKWICDYICYQCSRPPPAHSKDLHSTI 1066
|.|.|:.|:::||||||||||||::.:. .|:.:.|||:..:|.||.||||||.|.||:||||.|
Mouse 790 LNSQWRQDMSISLAALELLSGLAKVKVM-VDSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMI 853
Fly 1067 VAAFQCTAAWLMQHPYLLQDKDCLQTVLEVVELGISGTKSQSKGTDIPKFKDEKELKPASMRVRD 1131
||||||...||.:||.:|.:||||:.|||:|||||||:||::...:: |:|.:||..||||||:|
Mouse 854 VAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEV-KYKGDKEPNPASMRVKD 917
Fly 1132 AAENLLTIILEQVGYFPSECGPESISSLLDELALMKHCNSMVPAAAASSEQAIAKFKYFVTENST 1196
|||..||.|::.:|.|||..||.|..||::|..|:|: |.:|.....| |:|||.:||.
Mouse 918 AAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKY--SRLPTINKHS------FRYFVLDNSV 974
Fly 1197 ILALLEEPLGNDQ-DPQPTVTLLIRGPFGRHAWTMQLRHLPR-SKSGIKYHAINPGRPIPMNDVT 1259
|||:||:||||:| |..|:||:|:||..||.||..||..||| :|:..|.....| ||:|.|||.
Mouse 975 ILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEP-RPVPKNDVG 1038
Fly 1260 QRLDSEQKNFPDGVDKVQPCVADYSIPTIEQMREQYGTAVIRELESLLENQSIHEKLAWAEADTS 1324
.:...:.:.||:.|||:....||.|||.:.:: |..|||.. ||||....|...
Mouse 1039 FKYSVKHRPFPEEVDKIPFVKADLSIPDLHEI-------VTEELEER------HEKLRSGMAQQI 1090
Fly 1325 ADSLSHAQ----------------ECVPPTVCHEFHAARLFLSHFGFLGFET-RNPQNPAEALGN 1372
|..:...| :|.||....||..|||||||||||..|. :.|.|.. .
Mouse 1091 AYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSR----L 1151
Fly 1373 PPQRPLIVLDTKSAAFAADLDRLDKLSARTHDSVYVFYVKSGQTSAQQIIANMGEESSASHDPHF 1437
||. ||.||:....|..|:..||.|..|..|:|::||:|.||.:.|:|:.|: |||.:..|||
Mouse 1152 PPH--LIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRNVQPHF 1212
Fly 1438 ASMLQTLGWPVQVSEHSGWTGFAHNSWSL------KGTPEEQLKST--ANELNYNGSQRVLYWAD 1494
...|.:|||.|.|.:|.||||....|||: :|:..:::.|: .....:||.::|||:||
Mouse 1213 LEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCDDGEGSEPDEITSSEDVGASIFNGQKKVLYYAD 1277
Fly 1495 VSSEIAFVVPTTWNLRYNSDTCDSGSISSTDQIGSSNVWTRGEADSAAGLAKSKSRNLSLELDTN 1559
..:|||||||:. :...:|:.:| :.:||...||: |...|:.|... |:|||..|
Mouse 1278 ALTEIAFVVPSP--VESLTDSLES---NISDQDSDSNM------DLMPGILKQPP--LTLELVPN 1329
Fly 1560 RRD-------------VKE-----PVPPTRRKGNVTKPTLLAQAPAKIFLVWLESYEDYLNFPLE 1606
..| :|: ||||. |..| ::.:||:|.|:|..||||.
Mouse 1330 HTDSLNSSQRLSPSSRMKKLPQGRPVPPL---GPET----------RVSVVWVERYDDIENFPLS 1381
Fly 1607 DLLAYTRTGEE--------LQTQQLPRASDCHVIFVHSLLSGLLRVKLQGPPGRMSFATPLVDGM 1663
||:....||.| |::..|.: :..|||:|.|.:||.|:|:||..|:.:...||||||
Mouse 1382 DLMTEISTGVETTANSSTSLRSTTLEK--EVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGM 1444
Fly 1664 VLSRRVVGNLVRQTALNISRRRRLDNDNYQPPHVRRRLKVQDIVQKYKMDLSEADLLAHLFQ 1725
::|||.:|.|||||.:||.||:||::|:|.||||||:.|:.|||.||:....|.:....|||
Mouse 1445 IVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQ 1506
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