DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATPsyndelta and ATP5F1D

DIOPT Version :9

Sequence 1:	NP_001259397.1	Gene:	ATPsyndelta / 31950	FlyBaseID:	FBgn0028342	Length:	157	Species:	Drosophila melanogaster
Sequence 2:	NP_001001975.1	Gene:	ATP5F1D / 513	HGNCID:	837	Length:	168	Species:	Homo sapiens

Alignment Length:	154	Identity:	75/154 - (48%)
Similarity:	102/154 - (66%)	Gaps:	1/154 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VKNARLLAARGARLAQNRSYSDEMKLTFAAANKTFYDAAVVRQIDVPSFSGSFGILAKHVPTLAV 68
            |::||..|...|..|. .|..::|..|||:..:.|::.|.|||:|||:.:|:|||||.|||||.|
Human    16 VRHARAYAEAAAAPAA-ASGPNQMSFTFASPTQVFFNGANVRQVDVPTLTGAFGILAAHVPTLQV 79

  Fly    69 LKPGVVQVVENDGKTLKFFVSSGSVTVNEDSSVQVLAEEAHNIEDIDANEARQLLAKYQSQLSSA 133
            |:||:|.|...||.|.|:||||||:.||.|||||:|||||..::.:|...|:..|.|.|::|...
Human    80 LRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQAELVGT 144

  Fly   134 GDDKAKAQAAIAVEVAEALVKAAE 157
            .|:..:|:..|.:|..||||||.|
Human   145 ADEATRAEIQIRIEANEALVKALE 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsyndelta	NP_001259397.1	F1-ATPase_delta	27..141	CDD:213395	58/113 (51%)
ATP5F1D	NP_001001975.1	F1-ATPase_delta	38..162	CDD:213395	61/123 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152380
Domainoid	1	1.000	104	1.000	Domainoid score	I6739
eggNOG	1	0.900	-	-		E1_COG0355
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37514
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4575
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53851
OrthoDB	1	1.010	-	-		D1286602at2759
OrthoFinder	1	1.000	-	-		FOG0003148
OrthoInspector	1	1.000	-	-		oto88657
orthoMCL	1	0.900	-	-		OOG6_101225
Panther	1	1.100	-	-	LDO	PTHR13822
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R119
SonicParanoid	1	1.000	-	-		X4680
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800