Protein Alignment LysRS and KRS1

DIOPT Version :10

• Sequence 1: NP_727353.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_010322.1
• Gene: KRS1 / 851607
• SGDID: S000002444
• Length: 591
• Species: Saccharomyces cerevisiae
• Alignment Length: 559
• Identity: 341/559 - (61%)
• Similarity: 433/559 - (77%)
• Gaps: 15/559 - (2%)

  Fly    42 TKLELKRRLKAEQ-KAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSP 105
            :|.|||:|:|..| :||:.|:||||.|  ..|.|||:...  .::.|::||:.||..:|||:::.
Yeast    28 SKSELKKRIKQRQVEAKKAAKKAAAQP--KPASKKKTDLF--ADLDPSQYFETRSRQIQELRKTH 88

  Fly   106 ATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKV 170
            ..:|||||||||.|..:|:|||.: ||:||||...|:|:|||:||.||||:||.||.|.|:||:|
Yeast    89 EPNPYPHKFHVSISNPEFLAKYAH-LKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEV 152

  Fly   171 QVMASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTK-----KGELSVMPSEIKLLSPCLHMLP 230
            |:|:..:.|.....:|.|...|:||||:||.|:.|:|:     :||:||..|.::||:|||||||
Yeast   153 QLMSQLQDYCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLP 217

  Fly   231 HLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIAGGAT 295
            ..|||.||:|||||:||||||:|.:.|.:|..|::||.|:|:|||:..|:|:||||||:||||||
Yeast   218 ADHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGAT 282

  Fly   296 AKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAY 360
            ||||:||||||.||::|||||||:.|.||||||||||||||||||||||:||||||||||||.||
Yeast   283 AKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEFYQAY 347

  Fly   361 ADYADIMDITEQLVSGMVKAIRGSYKVIYHPEGPEGP--EQELDFTPPFKRVSMIKTLEEKLQVK 423
            ||..|:||:||.:.|.|||.|.|||.:.|||: |..|  |.||:|:.|:||::||:.||:...||
Yeast   348 ADVYDLMDMTELMFSEMVKEITGSYIIKYHPD-PADPAKELELNFSRPWKRINMIEELEKVFNVK 411

  Fly   424 FPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPL 488
            ||:.|..::.||.:||.::...:::|||.|.|.||:||||||| :|:.|:|||||..|||:||||
Yeast   412 FPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDKLVGE-LEDTCINPTFIFGHPQMMSPL 475

  Fly   489 AKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSL 553
            |||.|..|||.||||:|||.|||||||||||||..||.|||:||..|..||||||||||.||.:|
Yeast   476 AKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQKDQGDDEAQLVDETFCNAL 540

  Fly   554 EYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFPAMKPE 592
            |||||||||:|.|||||||||||||.|:||||||.:||:
Yeast   541 EYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFPTLKPD 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_727353.1	PLN02502	42..593	CDD:215278	341/559 (61%)
KRS1	NP_010322.1	PLN02502	24..579	CDD:215278	340/557 (61%)