Protein Alignment LysRS and kars1

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_012816251.2
• Gene: kars1 / 407964
• XenbaseID: XB-GENE-943468
• Length: 605
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 395/563 - (70%)
• Similarity: 467/563 - (82%)
• Gaps: 7/563 - (1%)

  Fly    43 KLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSPAT 107
            |.|.|||||||:||   .||.|....:|.....:.:|.:||.:.||:|||:|:.|:|:|| ....
 Frog    45 KSEQKRRLKAEKKA---TEKEAKHKEQNEKLHTEEAAIDEETLDPNQYFKIRTQAIQQLK-GTKD 105

  Fly   108 DPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQV 172
            ||||||:||..||.::|.|| |:|:.|:.|..| :|:|||:||.|.||||||||||||||.|:||
 Frog   106 DPYPHKYHVDMSLTEYIQKY-NNLQTGDQLSEV-VSIAGRIHAKRISGAKLIFYDLRGEGTKLQV 168

  Fly   173 MASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGELSVMPSEIKLLSPCLHMLPHLHFGLK 237
            ||:::.||||.:|....:||||||:|||.|:||||||||||::|.|:.|||||||||||||||||
 Frog   169 MANSRFYKSEEEFATINNKLRRGDLIGVKGNPGKTKKGELSIIPHEMILLSPCLHMLPHLHFGLK 233

  Fly   238 DKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIAGGATAKPFVTH 302
            ||||||||||||||||:.||:||.:|||:|:|:|:|||.||||||||||||:|.|||.||||:|:
 Frog   234 DKETRYRQRYLDLILNDYVRQKFIVRAKLITYLRKFLDDLGFLEIETPMMNVIPGGAVAKPFITY 298

  Fly   303 HNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYADIM 367
            ||:|.|.|:||||||||||||||||:|||||||||||||||||||||||||||||||||||.|:|
 Frog   299 HNELDMKLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYYDLM 363

  Fly   368 DITEQLVSGMVKAIRGSYKVIYHPEGPEGPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADTFNS 432
            :|||:|:|||||.|.|.||||||||||||||.|:||||||:|:||:..||:.|..|.||.|.|::
 Frog   364 EITEKLLSGMVKHITGGYKVIYHPEGPEGPEYEIDFTPPFRRISMVHELEKALGKKLPATDQFDT 428

  Fly   433 PETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRSIPG 497
            .||.:.|..:|.:.:||||||||||||||||||:|:|..|:|||:||:||||||||||:|||..|
 Frog   429 EETRKLLDDICVEKEVECPAPRTTARLLDKLVGDFLEVTCINPTYICDHPQIMSPLAKWHRSEKG 493

  Fly   498 LTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGG 562
            |||||||||.|||||||||||||||.|||.||.||..||||||||..:||.|||:||||||||.|
 Frog   494 LTERFELFVMKKEICNAYTELNDPVRQRELFEDQAKAKAAGDDEAMFIDETFCTALEYGLPPTAG 558

  Fly   563 FGMGIDRLAMFLTDSNNIKEVLLFPAMKPEDANRTAAETAPTA 605
            :||||||:||||||||||||||||||||||| |:....:.|.:
 Frog   559 WGMGIDRVAMFLTDSNNIKEVLLFPAMKPED-NKKDPNSTPNS 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	391/549 (71%)
		LysRS_N	141..250	CDD:239817	81/108 (75%)
		LysRS_core	253..591	CDD:238398	258/337 (77%)
kars1	XP_012816251.2	PLN02502	44..589	CDD:215278	391/549 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	577	1.000	Domainoid score	I219
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4053
Inparanoid	1	1.050	804	1.000	Inparanoid score	I486
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D258797at33208
OrthoFinder	1	1.000	-	-		FOG0002656
OrthoInspector	1	1.000	-	-		oto102816
Panther	1	1.100	-	-	LDO	PTHR42918
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1764
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160