Protein Alignment LysRS and krs1

DIOPT Version :10

• Sequence 1: NP_727353.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_595892.1
• Gene: krs1 / 2539746
• PomBaseID: SPBC17G9.03C
• Length: 591
• Species: Schizosaccharomyces pombe
• Alignment Length: 574
• Identity: 357/574 - (62%)
• Similarity: 435/574 - (75%)
• Gaps: 18/574 - (3%)

  Fly    31 VSAPQMEP---SKQTKLELKRRLKAE----QKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPN 88
            |.|..::|   .:.:|.|||:|.|..    .|||::|||||:||    ....|||:.:||::.|:
pombe    13 VKALVLDPVTGEQVSKTELKKREKQRARELAKAKKQAEKAASAP----VAAPKSSSKKEEDLDPS 73

  Fly    89 EYFKLRSAAVQELKRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRE 153
            :||:.||..:.||:::...:||||||.|:.:|.:|||||| .|..|||...|:::|||||..:|.
pombe    74 QYFENRSRTIMELRQTKDPNPYPHKFQVTITLPEFIAKYE-GLARGETKPEVEVAVAGRVLGLRT 137

  Fly   154 SGAKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTK-----KGELS 213
            :|.||.||::..:|.|:|||..|:. ....||......||||||||:.|:||::.     .||||
pombe   138 AGNKLRFYEIHADGKKLQVMCQAQD-ADTVDFAAQHEHLRRGDIIGIRGYPGRSNPKGRADGELS 201

  Fly   214 VMPSEIKLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLG 278
            :...:..||||||.|||..|:||||.|.|:||||||||:|.:.|::|.:|::||.|:|.|.|...
pombe   202 IFARQCVLLSPCLRMLPKEHYGLKDLEIRHRQRYLDLIMNRSTRDRFVMRSRIIQYIRHFFDSRD 266

  Fly   279 FLEIETPMMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGI 343
            |:|:||||||||||||||||||||||||.|||:||||||||.||||||||||||||||||||||.
pombe   267 FMEVETPMMNMIAGGATAKPFVTHHNDLDMDLYMRIAPELYLKMLVVGGLDRVYEIGRQFRNEGA 331

  Fly   344 DLTHNPEFTTCEFYMAYADYADIMDITEQLVSGMVKAIRGSYKVIYHPEGPEGPEQELDFTPPFK 408
            |||||||||:.|||.|||||.|:||.||:|:||:||.:.|||||.|||||||||:.||||:.|::
pombe   332 DLTHNPEFTSIEFYQAYADYYDLMDTTEELLSGLVKDLTGSYKVPYHPEGPEGPKWELDFSRPWR 396

  Fly   409 RVSMIKTLEEKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCV 473
            |::||:.|||||..|||..|..::||.|.||..|||||.|||..|:|.:||||||||||||..|:
pombe   397 RINMIEYLEEKLNTKFPPGDQLHTPEANAFLRDLCAKHGVECAPPQTCSRLLDKLVGEFIESECI 461

  Fly   474 NPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAG 538
            |||||..|||:||||||||||..||.||||.|||.||||||||||||...||.|||:||..||.|
pombe   462 NPTFIIGHPQMMSPLAKYHRSDAGLCERFEAFVATKEICNAYTELNDIFDQRARFEEQARQKAQG 526

  Fly   539 DDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFPAMKPE 592
            |||||::||||||:||||||||||:|||:|||.|||||||.|:||||||.||||
pombe   527 DDEAQIIDENFCTALEYGLPPTGGWGMGVDRLVMFLTDSNTIREVLLFPHMKPE 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_727353.1	PLN02502	42..593	CDD:215278	354/560 (63%)
krs1	NP_595892.1	PLN02502	23..580	CDD:215278	352/562 (63%)