Protein Alignment Fum4 and Fum2

DIOPT Version :10

• Sequence 1: NP_723527.1
• Gene: Fum4 / 318995
• FlyBaseID: FBgn0051874
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_727109.2
• Gene: Fum2 / 31606
• FlyBaseID: FBgn0029890
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 461
• Identity: 283/461 - (61%)
• Similarity: 366/461 - (79%)
• Gaps: 0/461 - (0%)

  Fly    24 RVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKKSAAETNKIHCLEEH 88
            |.|.|:.|.:.:|.|:::|.|||||.:.||||.:.||||.|:|:|:||:||:.||.||.:.|:..
  Fly    43 RTEKDTFGELKVPADKLYGAQTMRSKLNFPIGDIGERMPMPVIQAMGILKKACAEVNKDYGLDGK 107

  Fly    89 LCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEILGGQMGSKEPVDPN 153
            :.||:|.|||||||||||.:.||||||||.|||..||||.||||.|.||:::||::|||:||.||
  Fly   108 VSDAVSCACDDVISGKLYKQGHFPLVIWQTGSGTQTNMNTNEVISNAAIKMMGGELGSKKPVHPN 172

  Fly   154 EHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHLMDAVPLS 218
            :|||.:|||:|||.||:.|:|.|:|.|.|.|::....|.|..||:::.|:||||||||||||||:
  Fly   173 DHVNKSQSSNDTFPTAIHISVGMELNERLVPAVTHLRDALKSKSDEFKDIIKIGRTHLMDAVPLT 237

  Fly   219 LGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCIKRIAELTFLPFVES 283
            ||||||||.|||.||..|:...:.|:|:|.:|||:|||.::|:..::.:..|||:|||.||||.:
  Fly   238 LGQEFSGYTQQLTNGLERIKGCLPRVYELALGGTAVGTGLNTRKGFAEKVAKRISELTCLPFVSA 302

  Fly   284 PNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSSIMPGKVN 348
            ||.||:::|.|.:||:||.|||||.|:||||||||.||||||||.|||.||||||||||||||||
  Fly   303 PNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRLLGSGPRCGLGELMLPENEPGSSIMPGKVN 367

  Fly   349 PTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLGDGMKSFCTNCLEGI 413
            |||||:|:|:|||||||.|||::|||:|||:||.|.|::.|||||||.||.||..:|..||:||:
  Fly   368 PTQCESMTMLCAQVMGNQVAVTIGGSNGHFELNVFKPLVVSNVLRSIRLLADGSMTFSKNCVEGL 432

  Fly   414 EPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAILDGIQREDFREWVQPS 478
            :.|:.:|..|:.|||||||||:|||||:::|.|||.||.|.|||::||:..||..|.|:|||.|.
  Fly   433 QANKERIDKIMNESLMLVTALNPHIGYDKAALIAKTAHKNKTTLKEEALKTGITEEQFKEWVNPK 497

  Fly   479 KMLGPE 484
            :||||:
  Fly   498 EMLGPK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum4	NP_723527.1	Fumarase_classII	24..480	CDD:176465	279/455 (61%)
Fum2	NP_727109.2	FumC	42..501	CDD:439884	280/457 (61%)