Protein Alignment Fum4 and fum1

DIOPT Version :10

• Sequence 1: NP_723527.1
• Gene: Fum4 / 318995
• FlyBaseID: FBgn0051874
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_588397.3
• Gene: fum1 / 2539345
• PomBaseID: SPCC18.18C
• Length: 520
• Species: Schizosaccharomyces pombe
• Alignment Length: 459
• Identity: 241/459 - (52%)
• Similarity: 328/459 - (71%)
• Gaps: 3/459 - (0%)

  Fly    24 RVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKKSAAETNKIHCLEEH 88
            |.|.|:.|.:.:|.::.:|.||.|||..|.|||.:||:|.||::|.|::|::||..|:...|:..
pombe    59 RQESDTFGPIQVPAEKYWGAQTQRSLQNFRIGGEKERLPLPLVRAFGVLKRAAASVNREFGLDPK 123

  Fly    89 LCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEILGGQMGSKEPVDPN 153
            |.|||.:|..:||.|:|  :::||||::|.|||..:|||.||||.|||||||||.:|||:||.||
pombe   124 LADAIEQAAQEVIDGRL--DDNFPLVVFQTGSGTQSNMNSNEVIANRAIEILGGTLGSKKPVHPN 186

  Fly   154 EHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHLMDAVPLS 218
            :||||:|||:|||.|.:.||..:|:...|.|:::.....|..|..::.::|||||||:.||.|||
pombe   187 DHVNMSQSSNDTFPTVMHIASVLQIHTHLLPAMKHLHRALKGKEEEFKNIIKIGRTHMQDATPLS 251

  Fly   219 LGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCIKRIAELTFLPFVES 283
            ||||||||..|:..|..|::.|:.||..|..|||:|||.::|...:..:..:::::||.:.|..:
pombe   252 LGQEFSGYVTQVGYGIERINNALPRLCLLAQGGTAVGTGLNTFEGFDVKVAEKVSKLTNIEFKTA 316

  Fly   284 PNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSSIMPGKVN 348
            ||.||:::|.|.:||:.|.||.||.|:||||||||.||||||||.|||.||.|||||||||||||
pombe   317 PNKFEALAAHDAIVEMSGALNVIACSLMKIANDIRQLGSGPRCGLGELILPANEPGSSIMPGKVN 381

  Fly   349 PTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLGDGMKSFCTNCLEGI 413
            ||||||::|:||||||||..:::.|:|||.:||.|.|::|.|:|.||.||||..:||..:|:.||
pombe   382 PTQCEALTMVCAQVMGNHATITVAGASGHCELNVFKPLLAKNILSSIRLLGDACESFTDHCVVGI 446

  Fly   414 EPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAILDGI-QREDFREWVQP 477
            |||...|...:::||||||||:|||||:..|.|||.|..|.:||:.|.:..|. ..|.|.|||:|
pombe   447 EPNYEGIARHLRDSLMLVTALNPHIGYDNCAKIAKTALKNKSTLKHEFVTLGFGTPEQFDEWVRP 511

  Fly   478 SKML 481
            ..|:
pombe   512 ELMI 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum4	NP_723527.1	Fumarase_classII	24..480	CDD:176465	240/456 (53%)
fum1	NP_588397.3	FumC	57..515	CDD:439884	240/457 (53%)