Protein Alignment Fum4 and fh

DIOPT Version :10

• Sequence 1: NP_723527.1
• Gene: Fum4 / 318995
• FlyBaseID: FBgn0051874
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: XP_002935862.3
• Gene: fh / 100491219
• XenbaseID: XB-GENE-944116
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 269/476 - (56%)
• Similarity: 356/476 - (74%)
• Gaps: 4/476 - (0%)

  Fly    10 SLMYKLARLIVPDTRVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKK 74
            ||..|..|: ....|:|.|:.|.:.:|.|:.:|.||:||.|.|.||||.||||.|:|:|.||:|:
 Frog    25 SLTVKQGRM-ASSYRIESDTFGELQVPNDKYYGAQTVRSTMNFKIGGVTERMPVPVIRAFGILKR 88

  Fly    75 SAAETNKIHCLEEHLCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEI 139
            :|||.|:.:.|:.::.:.|.||.|:|.||||  ::|||||:||.|||..|||||||||.|||||:
 Frog    89 AAAEVNQDYGLDPNIANFIIKAADEVSSGKL--DDHFPLVVWQTGSGTQTNMNVNEVISNRAIEM 151

  Fly   140 LGGQMGSKEPVDPNEHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLI 204
            :||::|||:||.||:|||.:|||:|||.||:.||...::.|.|.|.|:...|.|.:||.::.::|
 Frog   152 MGGKLGSKDPVHPNDHVNKSQSSNDTFPTAMHIAAVKEVHEVLLPGLQKLHDALEEKSKEFENII 216

  Fly   205 KIGRTHLMDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCI 269
            ||||||..|||||:|||||.||.||:....:|:..|:.|:|:|..|||:|||.::|:..::.:..
 Frog   217 KIGRTHTQDAVPLTLGQEFGGYVQQIKYSVSRIKAALPRVYELAAGGTAVGTGLNTRIGFAEKVA 281

  Fly   270 KRIAELTFLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLP 334
            .::||||.|||:.:||.|||::|.|.||||.|.|||:|.|:|||||||||||||||.|.|||.||
 Frog   282 AKVAELTGLPFITAPNKFESLAAHDALVELSGALNTLACSLMKIANDIRFLGSGPRSGLGELILP 346

  Fly   335 ENEPGSSIMPGKVNPTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLG 399
            ||||||||||||||||||||::|:.|||||||||:::|.|:|||:||.|.|:|..|||:||.|||
 Frog   347 ENEPGSSIMPGKVNPTQCEAVTMVAAQVMGNHVAITIGCSNGHFELNVFKPVIIKNVLQSIRLLG 411

  Fly   400 DGMKSFCTNCLEGIEPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAILD 464
            |...||..||:.|::.|..:|..::.|||||||||:|||||:::|.|||.||..||||::.||..
 Frog   412 DAAVSFTDNCIVGVQANTERINKLMSESLMLVTALNPHIGYDKAAKIAKTAHKEGTTLKETAIKL 476

  Fly   465 GIQRED-FREWVQPSKMLGPE 484
            |....| |.:||:|..||||:
 Frog   477 GFLTSDQFDQWVKPEDMLGPK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum4	NP_723527.1	Fumarase_classII	24..480	CDD:176465	261/456 (57%)
fh	XP_002935862.3	FumC	34..495	CDD:439884	262/462 (57%)