Protein Alignment CG31674 and CTBP2

DIOPT Version :10

• Sequence 1: NP_610063.4
• Gene: CG31674 / 318878
• FlyBaseID: FBgn0051674
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_073713.2
• Gene: CTBP2 / 1488
• HGNCID: 2495
• Length: 985
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 89/335 - (26%)
• Similarity: 148/335 - (44%)
• Gaps: 40/335 - (11%)

  Fly     5 KPFKVLIAHTDVPPEGIEILKE-------QCEILQVINEPPKNRPEILEKIRGA---HAVIWGGR 59
            :|...|:...|...| :.|||:       ..:..|.|:|      ::|.:..||   |.:.....
Human   573 RPLVALLDGRDCTVE-MPILKDLATVAFCDAQSTQEIHE------KVLNEAVGAMMYHTITLTRE 630

  Fly    60 DILNAEILDAAGPQLKAVSTMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAARR 124
            |:   |...|    |:.:..:.||.:|||:....:.||.:.:.|:......||.|:..::...||
Human   631 DL---EKFKA----LRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRR 688

  Fly   125 -------FQEGRRKIDSDKWDKDHLNWMLGQDIRDSTVGFYGFGGIGQAVAKRLMGFDIKRMLYT 182
                   .:||.| :.|.:..::..:.  ...||..|:|..|||..|||||.|...|....:.|
Human   689 NTWLYQALREGTR-VQSVEQIREVASG--AARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFY- 749

  Fly   183 TRNRVSQD-IEERFNAKKV-DFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGR 245
              :...|| ||.....::| ..:.||.:||.:.:...|.:....|.|.....:|::.|.|||..|
Human   750 --DPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAAR 812

  Fly   246 GKIVNQDDLYEALKSNRIFAAGLDVMDPEPLP-SNDKLLTLDNVVVTPHVGYATRRTRVDAANLA 309
            |.:|::..|.:|||..||..|.|||.:.||.. :...|....|::.|||..:.:.:..::....|
Human   813 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAA 877

  Fly   310 SRNVLKGLAG 319
            :..:.:.:.|
Human   878 ATEIRRAITG 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31674	NP_610063.4	GDH	8..319	CDD:240626	87/330 (26%)
CTBP2	NP_073713.2	PHA03247	<109..572	CDD:223021
		PHA03377	<363..575	CDD:177614	0/1 (0%)
		CtBP_dh	574..892	CDD:240624	89/334 (27%)