Protein Alignment CG31643 and FASTKD5

DIOPT Version :9

• Sequence 1: NP_001285652.1
• Gene: CG31643 / 318867
• FlyBaseID: FBgn0051643
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_068598.1
• Gene: FASTKD5 / 60493
• HGNCID: 25790
• Length: 764
• Species: Homo sapiens
• Alignment Length: 820
• Identity: 146/820 - (17%)
• Similarity: 253/820 - (30%)
• Gaps: 290/820 - (35%)

  Fly   222 HINWCRSAEQVRLLSTCLFQLHFLIDEELFTRFKLRLTEMMQSGVLSSETPKALLKVIHMLNIPV 286
            ||:.|.||::|:.:.:.......|.........:...|...::..|...:|:|  ..:...::.|
Human    46 HISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRA--TGVDEEDVEV 108

  Fly   287 WSQTHTQLIREVMLVLRP--CIHQ---MESADLKSIC--RTFLH-------HQEPAALIEPLKKA 337
            :......   .|.|.|||  .:|.   .|::.|.|:.  ...||       :.:...:::.|.|
Human   109 FDSFENM---RVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCK- 169

  Fly   338 LEKLLQEE------GTADALFCAVPFATPLQRDQYLHQFKELLYSEEAWQQPNASGHLFSVLRA- 395
            |..|..|:      .|:.||.|            .|...|..|:..:         .|.:||:|
Human   170 LSSLPAEQHPVLLGSTSFALLC------------QLSVKKIQLFDTQ---------DLINVLKAF 213

  Fly   396 -----------LKVSDIEFCNTYWSGVVKELESCPEKHLHL-----RFLRHCQRYMNFNNNLGGT 444
                       |.|.:.:.|:..|...:.:|....:...:|     |||.....|:|.:
Human   214 VILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLH------ 272

  Fly   445 YRHLELERKLSRMCMNAIEHDIAGRLPAKFARLASFVLAY---------GQTPLAWKK----FPN 496
            ::.|.|.:.:..:.:......::..|..|   |.|.:|.|         |...|.:.|    ...
Human   273 WKDLSLSQLVHLIYVIGENRQVSQDLMQK---LESLILKYIDLINLEEVGTICLGFFKSSTNLSE 334

  Fly   497 FLLSKM--LAMAPQLGIQDCFLLSRGM-QIASELRFR----------------QHLPALAGMQLS 542
            |::.|:  ||.|   .||  .|.||.: .|....||.                |.:|:| |:| .
Human   335 FVMRKIGDLACA---NIQ--HLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSL-GVQ-G 392

  Fly   543 TMDSILIGCAERHLRDAEKDPLNASELSMIVRTLSHRKKLKNTVVYNQALAQYKNLHCNDLNSRV 607
            .|...|...|.|.|.:.   .:||...|:..|.                      .||   .|:.
Human   393 VMHLTLYCSALRFLNEG---VMNAVAASLPPRV----------------------AHC---RSKD 429

  Fly   608 VRDMAYNFNASNFFVPELLESMFAYISEQHDHVSGDTVEKVLTCSYNLGYMPASVEALNHASEVL 672
            |..:.::|...|:..|...|...:.|||.|..                  ||...:...|....|
Human   430 VAKILWSFGTLNYKPPNAEEFYSSLISEIHRK------------------MPEFNQYPEHLPTCL 476

  Fly   673 LRDFDQMSGLSVVQACLALCFYKSIPEQLINQVFCVKFIQRIEDEIQVCYSKATYPERVLNLVMQ 737
                            |.|.|.:..|.:||:......|::..::..:....|..|         .
Human   477 ----------------LGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELY---------T 516

  Fly   738 LNRTVCLDFPE--------------ANVPWFQQNYIEAQISKKSLIPSESTTEVKQLLHQLLQND 788
            |:.||.::.|:              :.:.|:        :::|.:.......|...||..:|...
Human   517 LDGTVGIECPDYRGNRLSTHLQQEGSELLWY--------LAEKDMNSKPEFLETVFLLETMLGGP 573

  Fly   789 KHFRCNHTTPYGYQIDFVIHFDRDKNPIP----APPVE--------------------------- 822
            ::.:.:...|:....|..:..|.:..|:|    |.|.|
Human   574 QYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKA 638

  Fly   823 -------------------------------------------------ATMLDRITKVAILLLK 838
                                                             |.|.....|:|:....
Human   639 RGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTN 703

  Fly   839 LDSFC--ENDLTALRGPESLKMRHLEMMGYKVMQINEHDW 876
            .:.:|  ..||..|   .::|.|.|..:||:|::::..:|
Human   704 RNQYCYGSRDLLGL---HNMKRRQLARLGYRVVELSYWEW 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31643	NP_001285652.1	FAST_1	647..713	CDD:284217	11/65 (17%)
		FAST_2	736..816	CDD:285557	13/93 (14%)
		RAP	834..894	CDD:214932	11/45 (24%)
FASTKD5	NP_068598.1	FAST_1	431..499	CDD:310980	18/101 (18%)
		FAST_2	514..601	CDD:312018	14/103 (14%)
		RAP	699..758	CDD:214932	11/45 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21228
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010