Protein Alignment CG31643 and Fastkd1

DIOPT Version :10

• Sequence 1: NP_723145.1
• Gene: CG31643 / 318867
• FlyBaseID: FBgn0051643
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_796218.2
• Gene: Fastkd1 / 320720
• MGIID: 2444596
• Length: 829
• Species: Mus musculus
• Alignment Length: 891
• Identity: 199/891 - (22%)
• Similarity: 391/891 - (43%)
• Gaps: 156/891 - (17%)

  Fly    69 PREQDALLTRLEEAKTGNQILDVLESCDG-LQSSHVVMGISLLWNIYHDAEQASKDAITDRV--- 129
            |...::|:|::::.....|:.|::|:... |....|....::||..........|:  .|.|
Mouse    19 PFSCESLITQMQKCTNEEQVFDLIETNTATLSEQQVGCAFNVLWQFQKQKTVLEKN--VDHVRNH 81

  Fly   130 -----LLNVLPKLAPYVHQLEIDDLSRCYLY-LRKMHIPNSEAVVEAVLTRSLQLIESQVDDEVI 188
                 |.::.....|.:....:.|:    || :::..:.:...::||::|.:.:.:| :.|..|
Mouse    82 PQFLTLCSITTNHIPAMSDATLVDV----LYSIKQFAVESHHPLIEALVTEAWKRLE-RFDTNV- 140

  Fly   189 PLTSLSRLSVGINLERDFFTPLVCRNFIPHLEHHIN-WCRSAEQVRLLSTCLFQLHFLIDEELFT 252
                ||..|..:..:..:|:||:.:     :...:| ...:.:.:|.||..:..:..||......
Mouse   141 ----LSIFSTCLADQHLYFSPLMGK-----IADIVNRRLETIQDLRALSVLMVSISSLISPCFQE 196

  Fly   253 RFKLRLTEMMQSGVLSSETPKALLKVIHMLNIPVWSQTHTQLIREVMLVLRPCIHQMESADLKSI 317
            |..:| ||::...|.||:...|...::.:.|:   ..:|..|:.....|.   |..|...||:||
Mouse   197 RLVIR-TELLFDTVNSSKVNIARRILLFLRNV---KYSHYPLLERCNQVF---IRNMSHLDLESI 254

  Fly   318 CRTFLHHQ----EPAALIEPLKKALEKLLQEEGTADA---LFCAVPFATPLQRDQYLHQFKE--L 373
            .:....:|    .....:|..:..|.::.......::   ||.|:   .|:.|.:...|.|.  |
Mouse   255 SKILNLYQFLQFHSFEFVEAARGRLAEMTLPSDHPESFVRLFAAL---GPVARPEIKKQLKSTIL 316

  Fly   374 LYSEEAWQQPNASGHLFSVLRALKVSDIEFCNTYWSGVVKELESCPEKHL----HLRFLRHCQ-- 432
            |.|||.     :|.....||.|::  |:|..|::   ::|::.|...|||    .:..|:..|
Mouse   317 LLSEEL-----SSQQALIVLGAME--DMESRNSH---LLKKIVSVLYKHLDNYKSIELLKIIQAL 371

  Fly   433 RYMNFNNNLGGTYRHLELERKLSRMCMNAIEHDIAGRLPAKFARLASFVLAYGQTPLAWKKFPNF 497
            .:::|.:.        ||..||..:.::.:|   |..:|::.:.|.|        .|:....|:.
Mouse   372 TFLHFQSK--------ELFMKLRELLLSRLE---ASVIPSEISVLVS--------ALSMLPHPHL 417

  Fly   498 ---LLSKMLAMAPQLGIQD----CFLLSRGMQIASELRFRQHLPALAGMQLSTMDSI-LIGCAER 554
               .:|::.|:.||...::    ...|.|.:|  |:|   ..|.:..|.||..:..: .:|   |
Mouse   418 SETAVSRIEAVLPQCDFRELNDLVVYLMRWIQ--SDL---VCLASTTGKQLDLLQKLDQLG---R 474

  Fly   555 H-LRDAEKDPLNASELSMIVRTLSHRKKLKNTVVYNQALAQYKNLHCNDLNSRVVRDMAYNFNAS 618
            | |:.:....|...||..:.....|...::.::.   ||.::    .::::...:..:|...:.:
Mouse   475 HRLQQSTNLDLLWEELKSLKGEWLHESLVEESIA---ALLRF----MDEIDYSNIAKVASFLSRT 532

  Fly   619 NFFVPELLESMFAYISEQHDHVSGDTVEKVLTCSYNLGYMPASVEALNHASEVLLRDFDQMSGLS 683
            |:....||:.:.:...:|        |||:...|.....:|.|:  ||:...    ..|:..| :
Mouse   533 NYLNTLLLDRIASVAIQQ--------VEKIHPFSVLAIILPFSI--LNYDPP----QKDEFFG-A 582

  Fly   684 VVQAC----------------LALCFYKSIPEQLINQVFCVKFIQRIEDEIQVCYSKATYPERVL 732
            .||.|                .:|...:..||.|:.::|.::|:.|::.::::..|..:  .|:.
Mouse   583 CVQCCNSYLGTLDPGTLVFLGFSLAVLEYFPEDLLKKMFNIEFLARLDSQLEILPSSLS--ARIQ 645

  Fly   733 NLVMQLNRTVCLDFPEANVPWFQQNYIEAQISKKSLIPSESTTEVKQLLHQLLQNDKHFRCNHTT 797
            ..:|:|||.|||:.||..||||...:.:.|.:|.:.:.:.:..::.::|.::|...:..:.:..:
Mouse   646 FRLMELNRAVCLECPELQVPWFHDRFCQRQFNKDTGVMNGAQQQIYKMLAEVLGGHQCVKPSALS 710

  Fly   798 PYGYQIDFVIHFDRDKNPIP------AP----------PVEATMLDRITKVAILLLKLDSFCEND 846
            ||.:.:.|....|:.|.|:|      ||          .||..:.....::||.||.:.:||.|
Mouse   711 PYYHTVGFECILDKRKKPLPYESHSIAPRKSLGMHWDSRVEPRLPPEAERIAIELLDVRAFCSN- 774

  Fly   847 LTALRGPESLKMRHLEMMGYKVMQINEHDWNSKYMASSTAKANYLK 892
            :..|:|..::|.||||::||:|:||...:|||..|::..|:.:||:
Mouse   775 IPHLKGKSAMKKRHLEILGYRVIQIPYFEWNSMAMSTKDARMDYLR 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31643	NP_723145.1	FAST_1	645..715	CDD:461999	20/85 (24%)
		FAST_2	735..817	CDD:462448	23/81 (28%)
		RAP	834..894	CDD:214932	25/59 (42%)
Fastkd1	NP_796218.2	RESC6-like	50..301	CDD:480594	53/277 (19%)
		RESC8-like	320..>615	CDD:467929	71/353 (20%)
		FAST_1	559..630	CDD:461999	16/77 (21%)
		FAST_2	647..730	CDD:462448	23/82 (28%)
		RAP	763..821	CDD:214932	25/59 (42%)