Protein Alignment CG31636 and TTPA

DIOPT Version :9

• Sequence 1: NP_001285685.1
• Gene: CG31636 / 318865
• FlyBaseID: FBgn0051636
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_000361.1
• Gene: TTPA / 7274
• HGNCID: 12404
• Length: 278
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 71/267 - (26%)
• Similarity: 107/267 - (40%)
• Gaps: 49/267 - (18%)

  Fly    18 ELNELPARMAQDIEALRDWVLKQPHLRAC---------------TDDQFLLAFLRGTKFSLERAK 67
            :||.||....          |.||.|.|.               ..|.|||.|||...|.|:.|.
Human    13 QLNALPDHSP----------LLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAW 67

  Fly    68 EKFDRFYTLQRSIPEVFNERRLATDPQVLDIVRM------GVLLQIPMDADDPGPRVTIIRAGSY 126
            .....:|..:...||:      :.|.....|:.:      |||    ...|..|.:|.|.|...:
Human    68 RLLKNYYKWRAECPEI------SADLHPRSIIGLLKAGYHGVL----RSRDPTGSKVLIYRIAHW 122

  Fly   127 DTSKHKFQDIIRVGSMFGEIMMFEDDNATVSGYVEIMDMAGVTGSHLFALQPQLLSKFSTYADEA 191
            |.......|:.||..:..|:::.|.:... :|...|.|:.|...||.|.:.|.:..|.:....::
Human   123 DPKVFTAYDVFRVSLITSELIVQEVETQR-NGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDS 186

  Fly   192 MPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISVSSDPAAIYELVRRKY----LPQEYGGT 252
            .|.:.:|||.||.|..|...|:.::.|...|||.||.:..:.   |:....::    ||.||||.
Human   187 FPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNN---YKQSLLQHFPDILPLEYGGE 248

  Fly   253 GGNLQDI 259
            ..:::||
Human   249 EFSMEDI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31636	NP_001285685.1	CRAL_TRIO_N	27..72	CDD:215024	15/59 (25%)
		SEC14	96..252	CDD:238099	45/165 (27%)
TTPA	NP_000361.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		4/6 (67%)
		CRAL_TRIO_N	<40..73	CDD:215024	10/32 (31%)
		CRAL_TRIO	99..248	CDD:395525	44/156 (28%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5	208..211		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010