Protein Alignment lz and RunxB

DIOPT Version :10

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_001259745.1
• Gene: RunxB / 33051
• FlyBaseID: FBgn0259162
• Length: 663
• Species: Drosophila melanogaster
• Alignment Length: 707
• Identity: 208/707 - (29%)
• Similarity: 288/707 - (40%)
• Gaps: 174/707 - (24%)

  Fly   213 SASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNNNNAVH----------- 266
            :|:..::......|:.::::.::.:|...:::..:||||:..:|:|:||||.|.
  Fly    38 TATTTTTKRRNAESSASSNNNNNNNTSTTNNNNTNNNNNSTTNNNNNNNNNNVKTKPVDTSPYLT 102

  Fly   267 -QDLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTI 330
             ::|:  ||.|.....|||||||:|.:|:.:|:.||.|||||||||:||||:||.||.|||.|||
  Fly   103 PENLI--ERTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTI 165

  Fly   331 RAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTV 395
            |||||||.|.||||.|..|||.|||||||||||||||||||||||.::|:|.|:|||.|||||||
  Fly   166 RAGNDENFCGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTV 230

  Fly   396 DGPREPRSKTSPTGGPHYRALG---LGQRPYIDGFPSTKA--LHELESLRRSA-----KVAAVTT 450
            |||||||||....|. |..|.|   .|..|.:.|.|....  .|.|..:....     :......
  Fly   231 DGPREPRSKVRHQGF-HPFAFGPQRFGPDPLMAGLPFKLPGFAHHLVGMHSHLHAPDWRAHMALG 294

  Fly   451 AAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGG-------------AGAGLVQQLSS 502
            ...||.|||......|||      .||..|    ..|::|.             |..|.....:|
  Fly   295 GRPAAFTAAPFFGHHAAA------FPTASG----LRGLSGDSQQHQQQQQQHQLATVGAAHSTTS 349

  Fly   503 NYSSPNSTINSDCQ----VYKP---NAPHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHHA 560
            ...||.:|..|..|    |..|   :.|.:.:.:.......:|.::||:              |.
  Fly   350 PEGSPTTTTTSGTQLSAFVQPPMTSSPPPVTSLQHDNNNNNSNNNNSSS--------------HI 400

  Fly   561 HAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAA 625
            .|..:..               |:.|.|:...       .:|..:.|     |...:....:..|
  Fly   401 DAGFESD---------------SISVTGSPRK-------SLGSPLTH-----DEEEAEAEAEAEA 438

  Fly   626 HLPAVLPEMHGHGFATDPYQTAGYGGGNTG----------GGS-------ASKSELDYGGSYNQA 673
            ...|...|....|.:.:       |||..|          ||:       :.|:..:..|.:..|
  Fly   439 EAEAEAEEAEVGGLSRN-------GGGIQGPLHSESSPGSGGAFTALIQRSGKNPTELFGGFAAA 496

  Fly   674 WSNGY--QNYQYGSCLATAQYGPQAAPPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQY 736
            ..|.:  ..:.:...||...:       .|.|      |.||     :...::..|:.|.....:
  Fly   497 GGNHFAPSGHSFNPALAAQLF-------LQSP------LLPQ-----SSQWLYTQLYGSYSDLPW 543

  Fly   737 LGTATSADHLTIGSLTGSSRSSI-EIGQDQYHQQV-----------HHAQQQQQQQQQQ------ 783
            |..|.:|....|.  .|...|.| .:|.:..|..|           |:....:......
  Fly   544 LRNAAAAAAANIN--PGQENSGIPPLGSNPDHDGVNLIKRCVTLITHNPPDAENANPNASPPVSS 606

  Fly   784 -------------QQVHHPQQQQVESAGEVGGSGAGG-VESAREEDVGDLSQVWRPY 826
                         ..|....:....|:|..||.|.|| |...|.......:.|||||
  Fly   607 TRRSPSPVETIDLDDVSTTSRSASGSSGHGGGVGGGGAVGPIRTRTPKPSADVWRPY 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	281..404	CDD:459963	94/122 (77%)
RunxB	NP_001259745.1	Runt	115..239	CDD:459963	94/123 (76%)