Protein Alignment lz and runx1

DIOPT Version :10

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_012813452.1
• Gene: runx1 / 100485449
• XenbaseID: XB-GENE-483164
• Length: 500
• Species: Xenopus tropicalis
• Alignment Length: 594
• Identity: 178/594 - (29%)
• Similarity: 227/594 - (38%)
• Gaps: 199/594 - (33%)

  Fly   282 EHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFT 346
            :||||||||.:|.||||.||.|||.|||||:|||||||.:|.|||.||:.||||||..|||||.|
 Frog    57 DHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNAT 121

  Fly   347 TQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREP-RSKTSPTGG 410
            ..|||.||:||||||||||||||||||||||.|:|||||||.:|||:|||||||| |.|..|..|
 Frog   122 AAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRPKYDPIIG 186

  Fly   411 PH----------YRALGLGQ-------------RPYIDGFPSTKA--------LHELESLRRSAK 444
            |.          |....||:             |..:|  ..||:        |.|||.|||:
 Frog   187 PGLVGGQIQAEIYSIYSLGKSADSSCVGSFTGHRQKLD--EQTKSGTLSFSERLSELEHLRRT-- 247

  Fly   445 VAAVTTAAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNS 509
                                 |...:....|||                           .:|.:
 Frog   248 ---------------------AMRVSPHHPTPT---------------------------PNPRA 264

  Fly   510 TINSDCQVYKPNAPHIQ-AAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHHAHAHLQHQMALPPP 573
            |:|............|| ..::..:..|:...|........:.:.||
 Frog   265 TLNHSTAFNPQPQSQIQDTRQVQASPPWSYDQSYQYLGSIATQSVHP------------------ 311

  Fly   574 PPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYD----SANSLEAGQYAAHLPAVL-PE 633
                 |.|:|.|...:..::...:.       :...|..|    |...:...:..:.||::. |.
 Frog   312 -----ATPISPGRASSMTSLSAELS-------SRLSGASDLTAFSDPRVGIDRQFSTLPSISDPR 364

  Fly   634 MHGHG-FATDPYQ-TAGYGGGNTGGGSASKSELDYGGSYNQAWSNGYQNYQYGSCLATAQYGPQA 696
            ||..| |...|.. |:|.|.|.:...||::                |..|
 Frog   365 MHYPGAFTYTPTPVTSGIGIGMSAMTSATR----------------YHTY--------------- 398

  Fly   697 APPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQYLGTATSADHLTIGSLTGSSRSSIEI 761
            .|||.|..              :|.|......||.....|.||:..:.| ....::|..||...|
 Frog   399 LPPPYPGS--------------SQAQSSPFQTSSPSYHLYYGTSAGSYH-QFSMMSGGDRSPPRI 448

  Fly   762 ---------GQDQYHQQVHHAQQQQQQQQQQQQVHHPQQQQVESAGEVGGSGAGGVESAREEDVG 817
                     |....:..:.:                 |...||:.|....|......:.|.|:.
 Frog   449 LPPCTNASTGSTLLNPNLPN-----------------QNDVVEAEGSHSNSPTNMGTTPRLEEA- 495

  Fly   818 DLSQVWRPY 826
                |||||
 Frog   496 ----VWRPY 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	281..404	CDD:459963	95/122 (78%)
runx1	XP_012813452.1	Runt	51..179	CDD:459963	94/121 (78%)
		RunxI	407..500	CDD:430037	23/115 (20%)