Protein Alignment lz and runx2

DIOPT Version :10

• Sequence 1: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_001128588.1
• Gene: runx2 / 100189546
• XenbaseID: XB-GENE-482021
• Length: 468
• Species: Xenopus tropicalis
• Alignment Length: 333
• Identity: 126/333 - (37%)
• Similarity: 168/333 - (50%)
• Gaps: 78/333 - (23%)

  Fly   282 EHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFT 346
            :||.|||||.:|..|||.||:|||.|||||:|||||||.||.||:.||:.||||||..||.||.:
 Frog    82 DHPAELVRTDSPNLLCSVLPSHWRCNKTLPVAFKVVALGEVSDGSVVTVMAGNDENYSAEPRNAS 146

  Fly   347 TQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPR--------S 403
            ..|||.||:||||||||||||||||||||||.|:|||||||.:|:|||||||||||        |
 Frog   147 AVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAMKVTVDGPREPRRHRQKLDDS 211

  Fly   404 KTS-----PTGGPHYRALGLG-----QRPYIDGFP-STKALHELESLRRS-------------AK 444
            |.|     ..|...:.::.:|     .||.::..| :.:...::...|::             :.
 Frog   212 KPSLFSERDLGRIPHPSMRMGVPPQSPRPSLNSSPFNPQGQSQIADPRQTQSSPPWSYDQSYPSY 276

  Fly   445 VAAVTTAAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLS-SNYSSPN 508
            ::.:|:.:..:.|..|:..  .....|::..|....|....|..:.......:..|: |.:|:|.
 Frog   277 LSQMTSPSIHSTTPLSSTR--GTGLPAISDVPRRLSGASELGPFSDPRQFTSISSLTESRFSNPR 339

  Fly   509 ----STINSDCQVYKPNAPHIQAAEMMGAGEWTNGSS--SSAAAYYHSHAHHPHAHHAHAHLQHQ 567
                :|.     .|.|..              |.|.|  .||..:||::
 Frog   340 MHYPATF-----TYSPPV--------------TTGMSLGMSATTHYHTY---------------- 369

  Fly   568 MALPPPPP 575
              ||||.|
 Frog   370 --LPPPYP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lz	NP_511099.2	Runt	281..404	CDD:459963	91/129 (71%)
runx2	NP_001128588.1	Runt	76..204	CDD:459963	91/121 (75%)
		PHA03247	<180..420	CDD:223021	54/235 (23%)
		RunxI	378..468	CDD:430037